18609-60-4

Upstream product

• 98-86-2 acetophenone 
• 109-94-4 formic acid ethyl ester 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 32042-38-9 2,2,2-trifluoroethyl formate 
• 1260421-90-6 3-phenylprop-2-yne-1,1-diyl bis(2,2-dimethylpropanoate) 

Downstream Products

• 15724-86-4 E-2-chlorovinyl phenyl ketone 
• 40685-20-9 (E)-3-methoxy-1-phenylprop-2-en-1-one 
• 13788-90-4 3,3-dimethoxy-1-phenylpropan-1-one 
• 27390-88-1 3-phenylpent-2-en-4-ynal 
• 104429-36-9 1-chloro-3-phenylpent-1-en-4-yn-3-ol 
• 104429-46-1 (Z)-6,6-Dimethyl-3-phenyl-hept-2-en-4-ynal 
• 104429-45-0 (Z)-3-phenylnon-2-en-4-ynal 
• 104429-44-9 (Z)-5-(4-methylphenyl)-3-phenylpent-2-en-4-ynal 
• 104429-39-2 (E)-1-Chloro-6,6-dimethyl-3-phenyl-hept-1-en-4-yn-3-ol 
• 104429-38-1 (E)-1-Chloro-3-phenyl-non-1-en-4-yn-3-ol 
• 104429-37-0 (E)-1-Chloro-3,5-diphenyl-pent-1-en-4-yn-3-ol 
• 87294-81-3 (E)-3,5-Diphenyl-hexa-2,5-dienal 
• 92-06-8 1,3-diphenylbenzene 
• 1006-67-3 5-phenylisoxazole 

Relevant academic research and scientific papers

Inorganic-organic heteropolyacid-gold(I) hybrids: Structures and catalytic applications

Gold(I)-polyoxometalate hybrid complexes 1-4 ([PPh3AuMeCN] xH4-xSiW12O40, x=1-4) were synthesized and characterized. The structure of the primary gold(I)- polyoxometalate 1 (x=1) was fully ascertained by XRD, FTIR, 31P and 29Si magic-angle spinning (MAS) NMR, mass spectroscopy, and SEM-energy dispersive X-ray spectroscopy (EDX) techniques. Moreover, this complex exhibited better catalytic activity and selectivity compared with standard, homogeneous, gold catalysts in the new rearrangement of propargylic gem-diesters. Gold(I)-polyoxometalate hybrid complexes ([AuPPh 3MeCN]xH4-xSiW12O40, x=1-4) were synthesized and characterized. [AuPPh3MeCN]H 3SiW12O40 exhibited better catalytic activity and selectivity compared with standard, homogeneous, gold catalysts in the new rearrangement of propargylic gem-diesters (see scheme).

Pyrazole and Isoxazole Derivatives as New, Potent, and Selective 20-Hydroxy-5,8,11,14-eicosatetraenoic Acid Synthase Inhibitors

In a previous paper, we reported the N-hydroxyformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor. Despite its attraction as a potential therapeutic agent for cerebral diseases, the preparation of an injectable formulation

Formylation of o-silylated enolates by Vilsmeier's reagent

Reaction of trimethylsilylenol ethers and Vilsmeier's reagent leads to the corresponding regiocontrolled β-dicarbonyl compounds with high to good yields.

First general method for direct formylation of kinetically-generated ketone enolates

(matrix presented) 2,2,2-Trifluoroethyl formate reacts rapidly at -78°C with preformed ketone enolates to give α-formyl ketones in good yields. In addition, this procedure allows for complete reversal of the regioselectivity of the classical Claisen react

STEREOSELECTIVE SYNTHESIS AND THERMAL BEHAVIOR OF (Z)-EPOXYHEXENYNES: A SIMPLE AND GENERAL ROUTE TO 2-VINYLFURANS

An efficient approach for the synthesis of 2,3-disubstituted furans (2a-j/3a-j) is described by using the thermally induced rearrangement of epoxyhexenynes (1a-j) which are prepared by streoselective synthesis of the (Z)-pentenynals 10 and subsequent Darz