186090-81-3

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 115-77-5 Pentaerythritol 
• 582300-82-1 5,5-bis(acetyloxymethyl)-2-(p-methoxyphenyl)-1,3-dioxane 
• 879015-71-1 acetic acid 2-acetoxymethyl-2-hydroxymethyl-3-(4-methoxy-benzyloxy)-propyl ester 
• 122788-52-7 5,5-bis(hydroxymethyl)-2-(4-methoxyphenyl)-1,3-dioxane 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 239089-26-0 (5-(((4-methoxybenzyl)oxy)methyl)-2,2-dimethyl-1,3-dioxan-5-yl)methanol 
• 1450912-09-0 3-hydroxy-2-hydroxymethyl-2-[(4-methoxybenzyloxy)methyl]propyl 4-methylbenzenesulfonate 
• 1450912-13-6 3-{1-[(tert-butyldimethylsilyl)oxy]prop-2-enyl}-3-[(4-methoxybenzyloxy)methyl]-oxetane 
• 1450912-12-5 1-{3-((4-methoxybenzyloxy)methyl)-oxetan-3-yl}prop-2-en-1-ol 
• 1450912-11-4 3-[(4-methoxybenzyloxy)methyl]-oxetane-3-carbaldehyde 
• 1450912-10-3 3-[(4-methoxybenzyloxy)methyl]-oxetan-3-ylmethanol 
• 879015-72-2 1-(p-methoxybenzyloxy)-3-(prop-2-ynyloxy)-2,2-bis[(prop-2-ynyloxy)methyl]propane 
• 18654-65-4 1-phytene 

Relevant academic research and scientific papers

CATIONIC LIPIDS

The present invention provides a technique that enables introduction of active ingredients, in particular, nucleic acids, into cells with superior efficiency; and cationic lipids, etc., for use in the technique. The compound or a salt thereof according to the present invention is a compound represented by formula (I) or a salt thereof. In formula (I), n represents an integer of 2 to 5, R represents a linear C1-5 alkyl group, a linear C7-11 alkenyl group, or a linear C11 alkadienyl group, and wavy lines each independently represent a cis-bond or a trans-bond.

Design and synthesis of novel 1,25-dihydroxyvitamin D3 analogues having a spiro-oxetane fused at the C2 position in the A-ring

Four structurally novel stereoisomeric analogues of 1,25-dihydroxyvitamin D3 (3a-d) bearing a spiro-oxetane fused at the C2 position of the A-ring have been designed and synthesised in a convergent manner. The requisite A-ring enyne precursors (13a,b) for the vitamin D analogues (3a,b) and (3c,d), respectively, were synthesised from pentaerythritol according to an eleven-step procedure. Preliminary biological evaluation of the analogues using the bovine thymus vitamin D receptor (VDR) suggested that the incorporation of the spiro-oxetane moiety instead of a gem-dimethyl group at the C2 position had a beneficial effect on the VDR affinity.

Synthesis of a nonavalent mannoside glycodendrimer based on pentaerythritol

A nonavalent glycodendrimer bearing terminal α-D-mannopyranoside units has been synthesized with a convergent approach. Terminal trivalent mannoside dendrons bearing p-halophenyl ethers were prepared by glycosylation of pentaerythritol derivatives having

Synthesis of new components for tethered bilayer membranes and preliminary surface characterization

Two analogues of the membrane-forming species PhCH2SS(C24H40O14)(C 20H41) (1) have been prepared via short synthetic routes. The compounds readily form self-assembled monolayers on gold.

Synthesis and application of α-D-mannosyl clusters as photoaffinity ligands for mannose-binding proteins: Concanavalin A as a model receptor

Mono-, di-, and tri-antennary α-D-mannopyranosyl derivatives were synthesized as oligosaccharide mimics. The compounds vary in the length of the acyclic aglyconic spacers linking, in the case of the di- and tri-antennary derivatives, the glycosyl endgroup