186196-06-5

Upstream product

• 654-01-3 (2,6-difluorophenyl)acetonitrile 
• 141-78-6 ethyl acetate 

Downstream Products

• 1242687-04-2 α-(2,4-difluorophenyl)-4-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazol-5-methanol 
• 1358582-74-7 5-[chloro(2,4-difluorophenyl)methyl]-4-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazole 
• 1621321-49-0 α-(2,4-difluorophenyl)-4-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazol-5-methanamine 
• 1621321-48-9 α-(2,4-difluorophenyl)-4-(2,6-difluorophenyl)-N,1,3-trimethyl-1H-pyrazol-5-methanamine 
• 1621321-50-3 4-(2,6-difluorophenyl)-5-[(2,4-difluorophenyl)(methylthio)methyl]-1,3-dimethyl-1H-pyrazole 
• 1243045-89-7 5-bromo-4-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazole 
• 1243046-83-4 4-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine 

Relevant academic research and scientific papers

APELIN RECEPTOR AGONISTS AND METHODS OF USE THEREOF

Provided herein are agonists of the apelin receptor for the treatment of disease. The compounds disclosed herein are useful for the treatment of a range of cardiovascular, renal and metabolic conditions.

FUNGICIDAL PYRAZOLES

Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein R1, R1a, R2, R3, R4, Q1 and Q2 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.