186347-96-6

Basic information

• Product Name: 2'-(triisopropylsilyl)-3'-dephenyl-3'-(2-methyl-1-propenyl)-7-(triethylsilyl)-10-(N,N-dimethylcarbamoyl)-14β-hydroxydocetaxel 1,14-carbonate
• Synonyms: 2'-(triisopropylsilyl)-3'-dephenyl-3'-(2-methyl-1-propenyl)-7-(triethylsilyl)-10-(N,N-dimethylcarbamoyl)-14β-hydroxydocetaxel 1,14-carbonate
• CAS NO: 186347-96-6
• Molecular Weight: 1169.56
• Mol File: 186347-96-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-(triisopropylsilyl)-3'-dephenyl-3'-(2-methyl-1-propenyl)-7-(triethylsilyl)-10-(N,N-dimethylcarbamoyl)-14β-hydroxydocetaxel 1,14-carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-(triisopropylsilyl)-3'-dephenyl-3'-(2-methyl-1-propenyl)-7-(triethylsilyl)-10-(N,N-dimethylcarbamoyl)-14β-hydroxydocetaxel 1,14-carbonate(186347-96-6)
• EPA Substance Registry System: 2'-(triisopropylsilyl)-3'-dephenyl-3'-(2-methyl-1-propenyl)-7-(triethylsilyl)-10-(N,N-dimethylcarbamoyl)-14β-hydroxydocetaxel 1,14-carbonate(186347-96-6)

Safety Data

• Hazardous Substances Data: 186347-96-6(Hazardous Substances Data)

Upstream product

• 156965-59-2 7-(triethylsilyl)-14β-hydroxy-10-deacetylbaccatin III 
• 178250-07-2 (3R,4S)-1-(4-methoxyphenyl)-3-triisopropylsiloxy-4-(2-methylprop-1-enyl)azetidin-2-one 
• 186347-83-1 7-Tes-1,14-carbonate-10-deacetylbaccatine III 
• 178250-11-8 (3R,4S)-1-tert-butoxycarbonyl-3-triisopropylsilyloxy-4-(2-methylprop-1-enyl)azetidin-2-one 
• 186347-88-6 7-(triethylsilyl)-10-(N,N-dimethylcarbamoyl)-14β-hydroxy-10-deacetylbaccatin III 1,14-carbonate 
• 178250-09-4 (3R,4S)-3-triisopropylsilyloxy-4-(2-methylpropen-2-yl)azetidin-2-one 
• 140236-11-9 N-(4-methoxyphenyl)-3-methyl-2-butenaldimine 
• 145533-34-2 14-β-hydroxy-10-deacetylbaccatin III 
• 24424-99-5 di-tert-butyl dicarbonate 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 994-30-9 triethylsilyl chloride 

Downstream Products

• 186348-11-8 3'-dephenyl-3'-(2-methyl-1-propenyl)-10-(N,N-dimethylcarbamoyl)-14β-hydroxydocetaxel 1,14 carbonate 

Relevant articles and documents

Syntheses and structure-activity relationships of taxoids derived from 14β-hydroxy-10-deacetylbaccatin III

A series of new taxoids derived from 14β-hydroxy-10-deacetylbaccatin III was synthesized by means of the β-lactam synthon method. Most of the new taxoids thus synthesized possess excellent cytotoxicity against human ovarian (A121), non-small-cell lung (A5