186348-22-1

Upstream product

• 186348-23-2 Bay-59-8862 
• 178250-07-2 (3R,4S)-1-(4-methoxyphenyl)-3-triisopropylsiloxy-4-(2-methylprop-1-enyl)azetidin-2-one 
• 186347-85-3 7,10-bis(triethylsilyl)-14β-hydroxy-10-deacetylbaccatin III 1,14-carbonate 
• 186347-83-1 7-Tes-1,14-carbonate-10-deacetylbaccatine III 
• 178250-09-4 (3R,4S)-3-triisopropylsilyloxy-4-(2-methylpropen-2-yl)azetidin-2-one 
• 178250-11-8 (3R,4S)-1-tert-butoxycarbonyl-3-triisopropylsilyloxy-4-(2-methylprop-1-enyl)azetidin-2-one 
• 140236-11-9 N-(4-methoxyphenyl)-3-methyl-2-butenaldimine 
• 156965-59-2 7-(triethylsilyl)-14β-hydroxy-10-deacetylbaccatin III 
• 145533-34-2 14-β-hydroxy-10-deacetylbaccatin III 
• 24424-99-5 di-tert-butyl dicarbonate 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 186348-08-3 3'-dephenyl-3'-(2-methyl-1-propenyl)-14β-hydroxydocetaxel 1,14 carbonate 

Downstream Products

• 916313-97-8 C₅₄H₈₃NO₁₆Si₂ 

Relevant academic research and scientific papers

Synthesis of a 11C-labelled taxane derivative by [1- 11C]acetylation

The 11C-labelling of the taxane derivative BAY 59-8862 (1), a potent anticancer drug, was carried out as a module-assisted automated multi-step synthesis procedure. The radiotracer [11C]1 was synthesized by reacting [1-11C

Syntheses and structure-activity relationships of taxoids derived from 14β-hydroxy-10-deacetylbaccatin III

A series of new taxoids derived from 14β-hydroxy-10-deacetylbaccatin III was synthesized by means of the β-lactam synthon method. Most of the new taxoids thus synthesized possess excellent cytotoxicity against human ovarian (A121), non-small-cell lung (A5