186384-08-7

Basic information

• Product Name: 1-(4-chlorophenyl)-3-(2'-hydroxy-3'-methoxymethyl-5'-methylphenyl)propane-1,3-dione
• Synonyms: 1-(4-chlorophenyl)-3-(2'-hydroxy-3'-methoxymethyl-5'-methylphenyl)propane-1,3-dione
• CAS NO: 186384-08-7
• Molecular Weight: 332.784
• Mol File: 186384-08-7.mol

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorophenyl)-3-(2'-hydroxy-3'-methoxymethyl-5'-methylphenyl)propane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-3-(2'-hydroxy-3'-methoxymethyl-5'-methylphenyl)propane-1,3-dione(186384-08-7)
• EPA Substance Registry System: 1-(4-chlorophenyl)-3-(2'-hydroxy-3'-methoxymethyl-5'-methylphenyl)propane-1,3-dione(186384-08-7)

Safety Data

• Hazardous Substances Data: 186384-08-7(Hazardous Substances Data)

Upstream product

• 1126-46-1 Methyl 4-chlorobenzoate 
• 87165-63-7 2'-hydroxy-5'-methyl-3'-methoxymethylacetophenone 
• 87165-62-6 3-chloromethyl-2-hydroxy-5-methyl acetophenone 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 

Downstream Products

• 186384-09-8 8-Bromomethyl-2-(4-chloro-phenyl)-6-methyl-chromen-4-one 

Relevant articles and documents

Synthesis and antitumour activity of new derivatives of flavone-8-acetic acid (FAA). Part 1: 6-methyl derivatives

A range of 17 derivatives of flavone-8-acetic acid (FAA) with a 6-methyl substituent have been prepared and their anti-tumour activity evaluated in vitro against a panel of human and murine tumour cell lines and in vivo against MAC 15A. While many of the compounds show activity comparable to FAA in vitro, this essentially disappears in vivo, possibly due to degradation before the compounds can reach the tumour site.