87165-62-6

Usage

Preparation

Preparation from 2-hydroxy-5-methylacetophenone by introduction of the chloromethyl group into aromatic ring by treatment with formaldehyde and hydrogen chloride at 70°.

Upstream product

• 50-00-0 formaldehyd 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 

Downstream Products

• 107700-23-2 O,O-dibutyl-S-(3-acetyl-2-hydroxy-5-methylbenzyl)phosphorodithioate 
• 107700-24-3 O,O-diisobutyl-S-(3-acetyl-2-hydroxy-5-methylbenzyl)phosphorodithioate 
• 107700-20-9 O,O-diethyl-S-(3-acetyl-2-hydroxy-5-methylbenzyl)phosphorodithioate 
• 93201-30-0 1-(3-Diethylaminomethyl-2-hydroxy-5-methyl-phenyl)-ethanone 
• 93201-31-1 1-{3-[(Diisopropylamino)-methyl]-2-hydroxy-5-methyl-phenyl}-ethanone 
• 107700-19-6 O,O-dimethylphosphorothiono-3-acetyl-2-hydroxy-5-methyl benzyl thiolate 
• 107700-22-1 O,O-diisopropyl-S-(3-acetyl-2-hydroxy-5-methylbenzyl)phosphorodithioate 
• 107700-21-0 O,O-dipropyl-S-(3-acetyl-2-hydroxy-5-methylbenzyl)phosphorodithioate 
• 87165-63-7 2'-hydroxy-5'-methyl-3'-methoxymethylacetophenone 
• 93201-35-5 3-(N,N-diisopropylaminomethyl)-2-methoxy-5-methylacetophenone 
• 160194-75-2 1-(3,5-dimethoxyphenyl)-3-(2'-hydroxy-3'-methoxymethyl-5'-methylphenyl)propane-1,3-dione 
• 160194-86-5 8-Bromomethyl-2-(3,5-dimethoxy-phenyl)-6-methyl-chromen-4-one 
• 160194-74-1 1-(2'-hydroxy-3'-methoxymethyl-5'-methylphenyl)-3-(3-methoxyphenyl)propane-1,3-dione 
• 186384-08-7 1-(4-chlorophenyl)-3-(2'-hydroxy-3'-methoxymethyl-5'-methylphenyl)propane-1,3-dione 

Relevant academic research and scientific papers

A water based method for hydroxymethylation of phenols and phenolic ketones

A water based eco-friendly method for the hydroxymethylation of phenols and phenolic ketones has in good yield been developed.

Synthesis and antitumour activity of new derivatives of flavone-8-acetic acid (FAA). Part 1: 6-methyl derivatives

A range of 17 derivatives of flavone-8-acetic acid (FAA) with a 6-methyl substituent have been prepared and their anti-tumour activity evaluated in vitro against a panel of human and murine tumour cell lines and in vivo against MAC 15A. While many of the compounds show activity comparable to FAA in vitro, this essentially disappears in vivo, possibly due to degradation before the compounds can reach the tumour site.

Synthesis and Insecticidal Acivity of 2-Hydroxy-3-(N,N-disubstituted-aminomethyl)-5-methylacetophenones

Some new 2-hydroxy-3-(N,N-disubstituted-aminomethyl)-5-methylacetophenones (3-8) have been prepared and evaluated for their insecticidal activity.These compounds have been found to be much more potent than 3-(N,N-disubstituted-aminomethyl)-4-hydroxyacetophenones (9-14).It appears that the removal of intramolecular hydrogen bond between phenolic hydroxyl and nitrogen lone pair increases the basicity and the insecticidal activity 3-8.