186424-40-8Relevant academic research and scientific papers
Conformationally restricted 1,5-diarylpyrazoles are selective COX-2 inhibitors
Bertenshaw, Stephen R.,Talley, John J.,Rogier,Graneto, Matthew J.,Koboldt, Carol M.,Zhang, Yan
, p. 2827 - 2830 (1996)
Benzothiopyranopyrazoles and benzopyranopyrazoles containing either a sulfone or sulfonamide moiety were synthesized and tested for COX-1 and COX-2 inhibition. This new class of COX-2 selective inhibitors possess antiinflammatory activity in vivo.
