1865-00-5

Basic information

• Product Name: Phenol, 2,6-dimethyl-, formate
• CAS NO: 1865-00-5
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Mol File: 1865-00-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phenol, 2,6-dimethyl-, formate(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,6-dimethyl-, formate(1865-00-5)
• EPA Substance Registry System: Phenol, 2,6-dimethyl-, formate(1865-00-5)

Safety Data

• Hazardous Substances Data: 1865-00-5(Hazardous Substances Data)

Upstream product

• 79-37-8 oxalyl dichloride 
• 576-26-1 2.6-dimethylphenol 
• 68-12-2 N,N-dimethyl-formamide 
• 25891-31-0 triformylamine 
• 64-18-6 formic acid 

Downstream Products

• 5470-34-8 4-methoxyformanilide 
• 33104-23-3 Dichlormethyl-2,6-dimethylphenylaether 

Relevant articles and documents

Solvent- and catalyst-free N-formylations of amines at ambient condition: Exploring the usability of aromatic formates as N-formylating agents

A solvent- and catalyst-free N-formylation protocol has been developed for amines (1s–21s) where aromatic formates (1r–6r) were used as the N-formylating agents. The amine substrates include both primary and secondary aromatic amines (1s–19s) as well as aliphatic amine (20s) and a primary amide (21s). Structures of both the aromatic formate and amine components strongly influenced the rate of the reaction and yield of the N-formamide products. The reaction condition is mild and easy to operate. This protocol can be done smoothly under ambient conditions and gives high yield of formamide products. Furthermore, the present method cannot be applied for the formylation of thiol group (22s). This signifies its possible use for the chemoselective N-formylation of amine in the presence of thiol functionality.

Orthoamides, LVI [1]. A new method of wide scope for the preparation of aryl formates

Aryl formates 4a-u, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26 are prepared by formylation of hydroxyarenes 3a-u, 5, 7, 9, 11, 13, 15, 17, 19, 21, 23, 25 with N,N-diformylacetamide (1) or triformamide (2), respectively, in fairly good yields. The reactions can be catalyzed by sodium diformamide or praseodymium(III) triflate. The thiolformate 28 was obtained analogously from 1-thionaphthol (27).