18651-21-3Relevant academic research and scientific papers
Synthesis of Diverse Oxa-Carbocycle-Annulated Flavones Using the Combined Claisen Rearrangement and Ring-Closing Metathesis
Gogula, Thirupathi,Yerrabelly, Jayaprakash Rao
, p. 547 - 557 (2016/07/22)
A simple and efficient route for the synthesis of oxepine-, oxocine-, oxepinone-, and dioxocine-angularly annulated flavone skeletons has been developed. The combined Claisen rearrangement and the ring-closing metathesis are used as key steps for the construction of C7/C8–C6–C6tricyclic core structures.
A facile synthesis of 2,3-dihydro-2-hydroxymethyl-5-arylfuro[2,3-h][1]benzopyran-7-ones
Parthasarathi Reddy,David Krupadanam
, p. 1253 - 1256 (2007/10/03)
The reaction of various 7-hydroxyflavones (1) with allyl bromide in potassium carbonate-acetone yielded the corresponding 7-allyloxy derivatives (2). Claisen rearrangement of 2 gives 7-hydroxy-8-allylflavones (3) which on reaction with equimolar quantity of mCPBA in dichloromethane furnish regioselectively 2,3-dihydro-2-hydroxymethyl-5-aryl-furo[2,3-h][1]benzopyran-7-ones (5) in good yields.
Synthesis of flavones and chromones having methyl substituent at 3-position
Bhat, V. S.,Joshi, V. S.
, p. 512 - 513 (2007/10/02)
3-Methyl-2-phenyl-4H-furobenzopyran-4-one (II) and 2,3-dimethyl-4H-furobenzopyran-4-one (III) have been synthesized from the corresponding 1-(2-hydroxy-3-benzofuranyl)propan-1-one (I). 8-Allyl-7-hydroxy-3-methyl-4Hbenzopyran-4-one (
