186532-64-9

Upstream product

• 4163-65-9 per-O-acetyl-α-D-mannopyranose 
• 82659-59-4 3-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)propene 
• 120520-79-8 2-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)ethyl aldehyde 
• 122920-03-0 2,6-Anhydro-7,8,9-trideoxy-D-glycero-D-manno-non-8-enitol 
• 98920-46-8 (2R,3R,4R,5R,6R)-2-(acetoxymethyl)-6-allyltetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 100-39-0 benzyl bromide 
• 617-04-9 (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 3879-79-6 (2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)-6-methoxytetrahydro-2H-pyran 

Downstream Products

• 204458-91-3 [2-((2R,3R,4R,5R,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-acetylamino]-acetic acid benzyl ester 
• 365418-23-1 ((2R,3R,4R,5R,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-acetic acid (1R,2S,3R)-2,3-bis-benzyloxy-1-benzyloxymethyl-pent-4-enyl ester 
• 365418-26-4 ((2R,3R,4R,5R,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-acetic acid (R)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-((4R,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-methyl ester 
• 365418-24-2 (2R,3R,4R,5R,6R)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-6-[2-((1R,2S,3R)-2,3-bis-benzyloxy-1-benzyloxymethyl-pent-4-enyloxy)-allyl]-tetrahydro-pyran 
• 194980-10-4 (S)-2-[2-((2R,3R,4R,5R,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-acetylamino]-pentanedioic acid dibenzyl ester 
• 204458-92-4 (S)-3-(4-Hydroxy-phenyl)-2-[2-((2R,3R,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-acetylamino]-propionic acid benzyl ester 

Relevant academic research and scientific papers

Carbon glycoside glycosylated tetravalent platinum compound as well as synthesis method and application thereof

The invention provides a carbon glycoside glycosylated tetravalent platinum compound, a synthesis method and application thereof. R1 and R2 are independently C1-C4 lower alkanes, R3 is glucose, galactose, mannose and ribose, different sugars are used as raw materials, and a series of carbon glycoside glycosylated tetravalent platinum compounds are synthesized through protection and deprotection reaction and metallization reaction of the sugars. The synthesis method is simple, the used raw materials are cheap and easy to obtain, the glycosylated tetravalent platinum compound has the capacity of targeting glucose transporter protein and has potential application value in the field of cancer treatment, introduction of a C-glucosidic bond enables the series of compounds to have the capacity of resisting hydrolysis of beta-glucosidase, and the compound is expected to be applied to the field of oral antitumor drugs.

Sites for dynamic protein-carbohydrate interactions of O- and C-linked mannosides on the E. coli FimH adhesin

Antagonists of the Escherichia coli type-1 fimbrial adhesin FimH are recognized as attractive alternatives for antibiotic therapies and prophylaxes against acute and recurrent bacterial infections. In this study α-D-mannopyranosides O- or C-linked with an

Synthesis and partial biological evaluation of a small library of differentially-linked β-C-disaccharides

The synthesis of a small library of differentially-linked β-C-disaccharides has been carried out through the use of a radical allylation-RCM strategy. Acids 6 were prepared by Keck allylation of a suitable carbohydrate-based radical precursor, followed by

Small molecules as structural and functional mimics of sialyl Lewis X tetrasaccharide in selectin inhibition: A remarkable enhancement of inhibition by additional negative charge and/or hydrophobic group

Several sialyl Lewis X (SLe(X))) mimics that contain the essential functional groups for receptor interaction and a negative charge or a hydrophobic group have been developed as inhibitors of E-, P-, and L-selectins. Some of the mimics exhibit selectin in

C-mannose derivatives as potent mimics of sialyl Lewis X

The synthesis of five sialyl Lewis X mimetics was described. Mimetics 2-6 were easily synthesized from readily available starting materials. Mimics 4 and 6 showed activities five-fold better than sialyl Lewis X. Copyright (C) 1996 Elsevier Science Ltd.