186707-36-8

Upstream product

• 100-52-7 benzaldehyde 
• 186031-94-7 (R)-5-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-pyrazolidin-3-one 
• 66601-82-9 methyl (S)-4,5-dihydroxy-4,5-O-isopropylidene-2-pentenoate 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 

Downstream Products

• 186707-40-4 (3R,5S)-2-Benzyl-5-methoxy-3-((S)-2-oxo-[1,3]dioxolan-4-yl)-pyrazolidine-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of enantiopure (nor)-azatropanes via N-acylhydrazonium ion intermediates

The synthesis of a number of aza-analogues of (nor)tropanes is described. Key features of the synthesis include the efficient preparation of an enantiopure 5-substituted 3-pyrazolidinone and stereoselective cyclization of an N-acylhydrazonium ion intermediate.