Synthesis of enantiopure (nor)-azatropanes via N-acylhydrazonium ion intermediates

DOI: 10.1016/S0040-4039(96)02241-1

Source and publish data:

Tetrahedron Letters p. 155 - 158 (1997)

Update date:2022-08-05

Topics:

Authors:

Teerhuis, N. Miranda

Hiemstra, Henk

Speckamp, W. Nico

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(96)02241-1

The synthesis of a number of aza-analogues of (nor)tropanes is described. Key features of the synthesis include the efficient preparation of an enantiopure 5-substituted 3-pyrazolidinone and stereoselective cyclization of an N-acylhydrazonium ion intermediate.

Full text of DOI:10.1016/S0040-4039(96)02241-1

Products guided by the article

Product name:(R)-1-Benzyl-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pyrazolidin-3-one

Cas No:186707-36-8

R&D Labs maybe for 186707-36-8

xuri chemicals co., ltd

Contact:86-516-66656369

Address:The west road of Huaihai, Xuzhou, China
AllyChem Co., Ltd., Dalian, China（BBChem）

Contact:+86-411-62313318/62313328

Address:No.5 of Jinbin Road, Jinzhou New District, Dalian City, Liaoning Province, P.R.China
Beijing Mashi Fine Chemical Co.,Ltd.

Contact:+86-10-61271592

Address:Room 506, Section B, Kaichi Mansion, Industrial Development
Acorn PharmaTech Co., Ltd

Contact:86-25-58619180

Address:Nanjing High-Tech Zone 10 Xinghuo Road Pukou District Nanjing, Jiangsu 210061 The People's Republic of China
Zhejiang Chemline International Co., Ltd.

Contact:+86-571-88062298

Address:Hengdian Industry Area, Dongyang, Zhejiang, China

Relevant to this article

Highly efficient and selective procedures for the synthesis of γ-alkylidenebutenolides via palladium-catalyzed ene-yne coupling and palladium- or silver-catalyzed lactonization of (Z)-2-en-4-ynoic acids. Synthesis of rubrolides A, C, D, and E

Doi:10.1055/s-1997-1513
(1997)
Efficient and chromatography-free methodology for the modular synthesis of oligo-(1H-pyrazol-4-yl)-arenes with controllable size, shape and steric bulk

Doi:10.1016/j.tetlet.2016.01.043
(2016)
(Salicylaldiminato)Ni(ii)-catalysts for hydrosilylation of olefins

Doi:10.1039/c5cy00270b
(2015)
Efficient construction of 8-membered ring framework of vinigrol through SmI₂-induced coupling cyclization

Doi:10.1016/S0040-4020(99)00885-6
(1999)
Chiral aziridinyl radicals: An application to the synthesis of the core nucleus of FR-900482

Doi:10.1021/jo961992n
(1997)
On the relation between polypeptide structure and spredptogenic activity. 1. Peptides of cystine

Doi:10.1002/hlca.19680510102
(1968)

Article Doi