186803-48-5Relevant articles and documents
Reinvestigation of the synthesis of (2R,3R) 2,3-(cyclohexylidenedioxy)-4-cyclopentenone as possible building block for the synthesis of carbocyclic nucleosides
Marien,Esmans,Lemiere,Dommisse
, p. 205 - 224 (2007/10/03)
An in depth study of the four-steps synthesis of (2R,3R) 2,3-(cyclohexylidenedioxy)-4-cyclopentenone (5) from D-ribonolactone (1) is described. From these experiments we must conclude that the overall yield reported in the literature (65%) is overestimated. All compounds have been throughly investigated by 1H- and 13C-NMR spectroscopy.
A new synthesis of D-ribonolactone from D-ribose by pyridinium chlorochromate oxidation
Liu,Caperelli
, p. 933 - 934 (2007/10/02)
2,3-O-Cyclohexylidene-D-ribonolactone is prepared directly from 2,3-O-cyclohexylidene-D-ribose by pyridinium chlorochromate (PCC) oxidation in 55-60% yield.