186830-60-4Relevant academic research and scientific papers
Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as antagonists of the NMDA receptor-channel complex
Grauert, Matthias,Bechtel, Wolf Dietrich,Ensinger, Helmut A.,Merz, Herbert,Carter, Adrian J.
, p. 2922 - 2930 (1997)
We have synthesized a series of stereoisomeric 6,7-benzomorphan derivatives with modified N-substituents and determined their ability to antagonize the N-methyl-D-aspartate (NMDA) receptor-channel complex in vitro and in vivo. The ability of the compounds
