192933-87-2Relevant academic research and scientific papers
Method of preparing norbenzomorphanes
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, (2008/06/13)
The present invention relates to a new process for preparing norbenzomorphan, the central intermediate step in the preparation of pharmaceutically useful benzomorphan derivatives of general formula 1 STR1 especially (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxy
Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as antagonists of the NMDA receptor-channel complex
Grauert, Matthias,Bechtel, Wolf Dietrich,Ensinger, Helmut A.,Merz, Herbert,Carter, Adrian J.
, p. 2922 - 2930 (2007/10/03)
We have synthesized a series of stereoisomeric 6,7-benzomorphan derivatives with modified N-substituents and determined their ability to antagonize the N-methyl-D-aspartate (NMDA) receptor-channel complex in vitro and in vivo. The ability of the compounds
