766489-46-7

Upstream product

• 19924-43-7 3-methoxyphenylacetonitrile 
• 186830-61-5 3-(2-Ethoxycarbonyl-ethylamino)-4-(3-methoxy-phenyl)-2,2-dimethyl-butyric acid ethyl ester 
• 186830-62-6 5-carboethoxy-3,3-dimethyl-2-(3-methoxyphenyl)methyl-4-piperidone 
• 186830-60-4 ethyl 3-amino-4-(3-methoxyphenyl)-2,2-dimethylbutanoate 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 707540-20-3 2-(3-methoxyphenyl)methyl-3,3-dimethyl-4-piperidone 

Downstream Products

• 192933-87-2 (+)-N-formyl-2-(3-methoxyphenyl)methyl-3,3-dimethyl-4-methylene-piperidine 

Relevant academic research and scientific papers

Method of preparing norbenzomorphanes

The present invention relates to a new process for preparing norbenzomorphan, the central intermediate step in the preparation of pharmaceutically useful benzomorphan derivatives of general formula 1 STR1 especially (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxy

Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as antagonists of the NMDA receptor-channel complex

We have synthesized a series of stereoisomeric 6,7-benzomorphan derivatives with modified N-substituents and determined their ability to antagonize the N-methyl-D-aspartate (NMDA) receptor-channel complex in vitro and in vivo. The ability of the compounds