1869-22-3

Basic information

• Product Name: 1-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]HYDRAZINE
• Synonyms: 2-CHLORO-5-(TRIFLUOROMETHYL)PHENYLHYDRAZINE;1-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]HYDRAZINE;1-[2-Chloro-5-(trifluoromethyl)phenyl]hydrazine, 95+%;2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL HYDRAZINE 95+%;4-Chloro-3-hydrazinobenzotrifluoride;TIMTEC-BB SBB001770;BUTTPARK 43\57-22
• CAS NO: 1869-22-3
• Molecular Formula: C₇H₆ClF₃N₂
• Molecular Weight: 210.58
• Mol File: 1869-22-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 65-68°C
• Boiling Point: 234.31 °C at 760 mmHg
• Flash Point: 95.508 °C
• Appearance: /
• Density: 1.487 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.05±0.10(Predicted)
• CAS DataBase Reference: 1-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]HYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]HYDRAZINE(1869-22-3)
• EPA Substance Registry System: 1-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]HYDRAZINE(1869-22-3)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-36/37/39
• Hazardous Substances Data: 1869-22-3(Hazardous Substances Data)

Usage

General Description

1-[2-Chloro-5-(trifluoromethyl)phenyl]hydrazine is a chemical compound with the molecular formula C7H6ClF3N2. It is a hydrazine derivative, which means it contains a central hydrazine functional group attached to a substituted phenyl ring. The compound is characterized by the presence of a chlorine atom and a trifluoromethyl group on the phenyl ring, which gives it unique chemical and physical properties. This chemical may have applications in organic synthesis, pharmaceuticals, and agrochemicals, and it is important to handle it with caution due to its potential reactivity and toxicity.

Upstream product

• 328-84-7 1,2-dichloro-4-(trifluoromethyl)benzene 
• 121-50-6 3-amino-4-chlorobenzotrifluoride 
• 98-38-4 2-Chloro-5-trifluoromethyl-benzenediazonium; chloride 

Downstream Products

• 39885-50-2 2-chloro-4-(trifluoromethyl)aniline 
• 121-50-6 3-amino-4-chlorobenzotrifluoride 
• 24095-89-4 C₉H₉ClF₃N₃S 
• 23152-52-5 C₉H₉ClF₃N₃O 
• 96423-58-4 N-(2-Chloro-5-trifluoromethyl-phenyl)-N'-(5,6-dihydro-4H-[1,3]thiazin-2-yl)-hydrazine; hydrochloride 
• 96423-46-0 N-(2-Chloro-5-trifluoromethyl-phenyl)-N'-(4,5-dihydro-thiazol-2-yl)-hydrazine; hydrobromide 

Relevant articles and documents

Discovery of a polysubstituted phenyl containing novel N-phenylpyrazole scaffold as potent ryanodine receptor activator

To develop the novel ryanodine receptors (RyRs) insecticides, encouraged by our previous research work, a series of novel N-phenylpyrazole derivatives containing a polysubstituted phenyl ring scaffold were designed and synthesized. The bioassays results i

Processes for preparing pesticidal intermediates

Compounds of formula (I) are prepared by hydrogenolysis of a compound of formula (II): where R1is haloalkyl, haloalkoxy or ?SF5; W is N or CR3; and R2and R3are H or Cl. The compounds of formula (I) can be used as intermediates in the preparation of pesticidally active arylpyrazole compounds.

Antiimplantation Agents: Part I - 1-Arylthiosemicarbazides

Several 1-arylthiosemicarbazides, 2-arylhydrazinothiazolines and 2-arylhydrazinodihydrothiazines have been examined for their antiimplantation activity in rats.Among the active compounds, 4-methyl-1-(3,5-bistrifluoromethylphenyl)thiosemicarbazide (3, C 2696-Go) and the corresponding 4,4-dimethyl (47), ethyl (4), n-butyl (5) and allyl (6) derivatives completely inhibit implantation at doses 10, 3, 20, 20 and 30 mg/kg respectively.The 3,4-dichlorophenyl analogue (32) is effective at a dose of 30 mg/kg. 2-(3,5-Bistrifluoromethylphenyl)hydrazinothiazoline (51) and the corresponding dihydrothiazine (63) show a weaker activity.The biological profile of C 2696-Go has been investigated in detail.It appears to prevent implantation by its antiuterotropic activity and ability to inhibit desiduoma formation.