39885-50-2

Basic information

• Product Name: 4-Amino-3-chlorobenzotrifluoride
• Synonyms: 4-AMINO-5-CHLORO-BENZOTRIFLUORIDE;4-AMINO-3-CHLOROBENZOTRIFLUORIDE;3-CHLORO-4-AMINOBENZOTRIFLUORIDE;2-CHLORO-4-(TRIFLUOROMETHYL)ANILINE;BUTTPARK 29\06-52;TIMTEC-BB SBB003594;2-CHLORO-4-(TRIFLUOROMETHYL)ANILINE 97%;4-Amino-3-chlorobenzotrifluoride, 98% (2-Chloro-4-trifluoromethylaniline)
• CAS NO: 39885-50-2
• Molecular Formula: C₇H₅ClF₃N
• Molecular Weight: 195.57
• EINECS: 254-674-8
• Product Categories: Aromatic Halides (substituted);Fluorochemicals
• Mol File: 39885-50-2.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 214-218 °C(lit.)
• Flash Point: 218 °F
• Appearance: clear light yellow to yellow liquid after melting
• Density: 1.4160 g/mL at 25 °C(lit.)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: n20/D 1.5030(lit.)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 0.82±0.10(Predicted)
• BRN: 4179703
• CAS DataBase Reference: 4-Amino-3-chlorobenzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-chlorobenzotrifluoride(39885-50-2)
• EPA Substance Registry System: 4-Amino-3-chlorobenzotrifluoride(39885-50-2)

Safety Data

• Hazard Codes: Xi,Xn,N,T
• Statements: 36/37/38-20/21/22-50-24-20/22
• Safety Statements: 26-36-36/37/39-23-61-45
• RIDADR: UN2810
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 39885-50-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H6BrNO/c10-7-3-1-2-6-8(12)4-5-11-9(6)7/h1-5H,(H,11,12)

Upstream product

• 328-84-7 1,2-dichloro-4-(trifluoromethyl)benzene 
• 2314-97-8 iodotrifluoromethane 
• 95-51-2 o-chloroaniline 
• 31825-28-2 2-chloro-4-trichloromethylphenyl isocyanate 
• 455-14-1 4-trifluoromethylphenylamine 
• 86398-98-3 2-chloro-4-trifluoromethylphenyl hydrazine 
• 1869-22-3 [2-Chloro-5-(trifluoromethyl)phenyl]hydrazine 
• 75-63-8 Bromotrifluoromethane 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 39886-31-2 5-methyl-oxazolidine-3-carboxylic acid (2-chloro-4-trifluoromethyl-phenylcarbamoyl)-amide 
• 401567-22-4 6-trifluoromethyl-1,3-benzothiazole-2-thiol 
• 105420-30-2 N-(2-chloro-4-trifluoromethylphenyl)-3-trifluromethylbenzenesulfonamide 
• 24279-39-8 2,6-dichloro-4-(trifluoromethyl)aniline 
• 1115300-94-1 1-azido-2-chloro-4-(trifluoromethyl)benzene 
• 934192-70-8 5-chloro-N-(2-chloro-4-(trifluoromethyl)phenyl)-2-hydroxybenzamide 

Relevant articles and documents

In situ Generation of Hypervalent Iodine Reagents for the Electrophilic Chlorination of Arenes

Efficient metal-free methods for the electrophilic chlorination of arenes using PIFA and simple chlorine sources are reported. The in situ formation of PhI(Cl)OCOCF3 from PIFA and KCl is proposed, which resulted in a chlorinating species for moderately activated arenes. Moreover, the in situ formation of PhICl2 from PIFA and TMSCl resulted in an excellent approach for the chlorination of a great variety of arenes (20 examples) in high yields, even when working on a multigram scale.

PROCESS FOR SYNTHESIS FIPRONIL

The present disclosure relates to a process for trifluoromethylsulfinyl pyrazole compound of formula I, from a compound of formula III, wherein, R, R1 and R2 represent a group containing halogen group respectively and R3 represents a perhaloalkyl.

PROCESS FOR PREPARING POLYHALOGENATED PERHALOALKYLANILINE

A method for preparing polyhalogenated p-trifluoromethylanilines, especially 2,6-dihalo-p-trifluoromethylaniline is provided The method comprises reacting ammonia with 3,4-dihalobenzotrifluoride at a temperature ranging from 200 °C to 300 °C in the presence of an alkali halide, and then halogenating the resultant intermediates with halogenating agents like sulfuryl chloride, chlorine and PC15 to get 2,6-dihalo-p-trifluoromethylaniline.