187035-29-6

Basic information

• Product Name: 1-Pyrrolidinamine,2-(methoxymethyl)-(9CI)
• Synonyms: 1-Pyrrolidinamine,2-(methoxymethyl)-(9CI);2-(methoxymethyl)pyrrolidin-1-amine
• CAS NO: 187035-29-6
• Molecular Formula: C6H14N2O
• Molecular Weight: 130.18816
• Product Categories: PYRROLIDINE;AMINEPRIMARY
• Mol File: 187035-29-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Pyrrolidinamine,2-(methoxymethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinamine,2-(methoxymethyl)-(9CI)(187035-29-6)
• EPA Substance Registry System: 1-Pyrrolidinamine,2-(methoxymethyl)-(9CI)(187035-29-6)

Safety Data

• Hazardous Substances Data: 187035-29-6(Hazardous Substances Data)

Upstream product

• 147-85-3 L-proline 
• 63126-45-4 (S)-2-(methoxymethyl)pyrrolidine-1-carbaldehyde 
• 55456-46-7 (S)-(-)-1-Formyl-2-(hydroxymethyl)pyrrolidine 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 95312-82-6 (S)-(-)-1-carbamoyl-2-methoxymethylpyrrolidine 
• 108439-26-5 (3S,4S)-4-{[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-methyl}-3,5-diphenyl-pentanoic acid methyl ester 
• 89999-42-8 (S)-2-methoxymethyl-1-(3-phenylpropylidenamino)pyrrolidine 
• 60096-50-6 (S)-N-Nitroso-O-methylprolinol 
• 344-25-2 D-Prolin 
• 578741-08-9 (R)-(+)-1-carbamoyl-2-methoxymethylpyrrolidine 
• 121817-72-9 (R)-2-(methoxymethyl)pyrrolidine hydrochloride 
• 121817-71-8 (R)-(+)-2-(methoxymethyl)-1-pyrrolidinecarboxaldehyde 
• 68832-13-3 D-prolinol 
• 72748-98-2 (R)-2-Methoxymethyl-1-nitroso-pyrrolidine 

Downstream Products

• 686319-72-2 C₁₈H₂₇N₃O 
• 686319-73-3 C₁₃H₂₄N₄O 
• 1469876-30-9 C₁₇H₂₆N₄O 
• 686319-69-7 C₁₃H₂₂N₂OS 
• 1469876-29-6 C₁₃H₂₁ClN₂OS 
• 686319-68-6 C₁₄H₂₅N₃O 

Relevant articles and documents

Selective reduction of N-nitroso aza-aliphatic cyclic compounds to the corresponding N-amino products using zinc dust in CO2–H2O medium

[Figure not available: see fulltext.] A new method for reduction of N-nitroso aza-aliphatic cyclic compounds employing zinc in pressurized CO2–H2O medium has been developed. H2O and NH4Cl were used as hydrogen donors, and reduction was performed under environmentally benign conditions. The presented approach allowed to obtain the respective N-amino products selectively and in excellent yields (up to 97%).

(S)-(-)-1-amino-2-methoxymethylpyrrolidine (SAMP) and (R)-(+)-1-amino-2-methoxymethylpyrrolidine (RAMP), versatile chiral auxiliaries

-

ASYMMETRIC MICHAEL ADDITIONS VIA SAMP-/RAMP-HYDRAZONES ANTI-DIASTEREO- AND ENANTIOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED 5-OXO-ALKANOATES

An efficient and highly anti-diastereo-(de=90-100percent) and enantioselective (ee=92-100percent) synthesis of 3,4-disubstituted 5-oxo-alkanoates 3 in good overall chemical yields is described.The procedure involves the asymmetric Michael addition of aldehydes or ketones to enoates via their lithiated SAMP-/RAMP-hydrazones.Both enantiomers are accessible at will.