187083-38-1

Basic information

• Product Name: 2-Pyrrolidinemethanol, 1-(2-azido-4,5-dimethoxybenzoyl)-, (2S)-
• CAS NO: 187083-38-1
• Molecular Formula: C14H18N4O4
• Molecular Weight: 306.321
• Mol File: 187083-38-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Pyrrolidinemethanol, 1-(2-azido-4,5-dimethoxybenzoyl)-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinemethanol, 1-(2-azido-4,5-dimethoxybenzoyl)-, (2S)-(187083-38-1)
• EPA Substance Registry System: 2-Pyrrolidinemethanol, 1-(2-azido-4,5-dimethoxybenzoyl)-, (2S)-(187083-38-1)

Safety Data

• Hazardous Substances Data: 187083-38-1(Hazardous Substances Data)

Upstream product

• 117573-59-8 2-azido-4,5-dimethoxybenzoic acid 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 147-85-3 L-proline 

Downstream Products

• 187083-45-0 (S)-1-(2-Azido-4,5-dimethoxy-benzoyl)-pyrrolidine-2-carbaldehyde 

Relevant articles and documents

Synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines by employing polymer-supported reagents: Preparation of DC-81

Polymer-supported reagents have been utilized for the generation of combinatorial library of substituted pyrrolo[2,1-c][1,4]benzodiazepine derivatives that provides a clean and efficient preparation and does not require conventional purification techniques like chromatography. This methodology involves intra molecular aza-Wittig reaction and has been extended for the synthesis of the natural product DC-81 in good overall yields.