187143-22-2

Basic information

• Product Name: 6-(Methylsulfonyl)-3-pyridinamine
• Synonyms: 6-(Methylsulfonyl)-3-pyridinamine
• CAS NO: 187143-22-2
• Molecular Formula: C6H8N2O2S
• Molecular Weight: 172
• Mol File: 187143-22-2.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 6-(Methylsulfonyl)-3-pyridinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(Methylsulfonyl)-3-pyridinamine(187143-22-2)
• EPA Substance Registry System: 6-(Methylsulfonyl)-3-pyridinamine(187143-22-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 187143-22-2(Hazardous Substances Data)

Usage

General Description

6-(Methylsulfonyl)-3-pyridinamine is a chemical compound with the molecular formula C6H8N2O2S. It is a derivative of pyridine and contains a sulfonyl group as well as a methyl group. 6-(Methylsulfonyl)-3-pyridinamine is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential anti-inflammatory and anti-tumor properties. Additionally, 6-(Methylsulfonyl)-3-pyridinamine is known to be a potent inhibitor of the enzyme cyclin-dependent kinase 9 (CDK9) and may have potential applications in cancer therapy. Overall, this chemical has a range of potential uses and is an important building block in the development of various products and medicines.

Upstream product

• 79134-11-5 3-Nitro-6-(methylsulfonyl)pyridine 
• 7439-89-6 iron 
• 20885-21-6 3-nitro-6-(methylthio)pyridine 
• 4548-45-2 2-chloro-5-nitropyridine 

Downstream Products

• 1198785-18-0 2-bromo-6-methanesulfonylpyridin-3-ylamine 
• 1156780-33-4 C₁₃H₁₄N₂O₂S 
• 1617508-26-5 N-(2,3-dimethoxybenzyl)-6-(methylsulfonyl)pyridin-3-amine 

Relevant articles and documents

METHODS OF USING INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS

This disclosure features the use of one or more indazole-3-carboxamide compounds or salts or analogs thereof, in the treatment of one or more diseases or conditions independently selected from the group consisting of a tendinopathy, dermatitis, psoriasis, morphea, ichthyosis, Raynaud's syndrome, and Darier's disease; and/or for promoting wound healing. The methods include administering to a subject (e.g., a subject in need thereof) a therapeutically effective amount of one or more indazole-3-carboxamide compounds or salts or analogs thereof as described anywhere herein.

SUBSTITUTED PYRAZOLE ANALOGUES AS RAR ANTAGONISTS

The present invention provides compounds of Formula I or a pharmaceutical salt thereof; methods of treating osteoarthritis and the pain associated with osteoarthritis using the compounds; and processes for preparing the compounds.

GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

Compounds of Formula I wherein R1, R2, X, and Y are as defined herein, or a tautomer, optical isomer, prodrug, co-crystal, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.