18735-96-1

Basic information

• Product Name: 2,7-dimethyl-2,3-dihydro-4H,5H-pyrano[4,3-b]pyran-4,5-dione
• Synonyms: 2,7-Dimethyl-2,3-dihydro-4H,5H-pyrano[4,3-b]pyran-4,5-dione; 4H,5H-pyrano[4,3-b]pyran-4,5-dione, 2,3-dihydro-2,7-dimethyl-
• CAS NO: 18735-96-1
• Molecular Formula: C₁₀H₁₀O₄
• Molecular Weight: 194.184
• Mol File: 18735-96-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 331.2°C at 760 mmHg
• Flash Point: 148.2°C
• Density: 1.29g/cm³
• Vapor Pressure: 0.000158mmHg at 25°C
• Refractive Index: 1.539
• CAS DataBase Reference: 2,7-dimethyl-2,3-dihydro-4H,5H-pyrano[4,3-b]pyran-4,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,7-dimethyl-2,3-dihydro-4H,5H-pyrano[4,3-b]pyran-4,5-dione(18735-96-1)
• EPA Substance Registry System: 2,7-dimethyl-2,3-dihydro-4H,5H-pyrano[4,3-b]pyran-4,5-dione(18735-96-1)

Safety Data

• Hazardous Substances Data: 18735-96-1(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic
It contains a ring structure with at least one ring having non-carbon atoms (such as oxygen) as part of the ring.

Structure

Pyrano-pyran
The compound has a fused ring system, with two pyran rings connected together.

Occurrence

Plant species
Coumarin is commonly found in various plant species.

Odor

Sweet, vanilla-like
The compound has a pleasant, sweet smell reminiscent of vanilla.

Applications

Perfumes and flavorings
Due to its pleasant smell, coumarin is used in the production of perfumes and flavorings.

Medicinal properties

Potential anticoagulant and anti-inflammatory effects
Coumarin is being studied for its possible health benefits, such as preventing blood clots and reducing inflammation.

Safety concerns

Liver toxicity
Coumarin has been linked to liver toxicity, so it should be used with caution to avoid potential harm.

Upstream product

• 130473-38-0 2,2-dimethyl-6-(2-oxo-2-methylethyl)-4H-1,3-dioxin-4-one 
• 136801-79-1 6-(2-hydroxypropyl)-2,2-dimethyl-4H-1,3-dioxin-4-one 
• 675-10-5 4-hydroxy-6-methyl-2-pyron 
• 10487-71-5 crotonyl chloride 
• 107-93-7 (E)-but-2-enoic acid 

Downstream Products

• 33176-11-3 2,7-dimethyl-4H-pyrano<3,2-c>-2H-pyran-4,5-dione 

Relevant articles and documents

Lewis acid mediated condensation reactions of α,β-unsaturated acids with 4-hydroxy-2-pyrones. A concise structural assignment of Fleischmann's α,α-bispyrone and Praill's α,γ-bispyrone

Unambiguous assignments of Fleischmann's α,α-bispyrone 3 and Praill's α,γ-bispyrone 6 have been carried out by exploring Lewis acid mediated condensation reactions of α,β-unsaturated carboxylic acids with 4-hydroxy- 2-pyrones. This protocol is shown to be useful for synthesis of a BCDE-ring tetracyclic analog of arisugacin. (C) 2000 Elsevier Science Ltd.

Synthesis of analogues and derivatives of radicinin of possible pharmaceutical interest

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