187396-97-0

Upstream product

• 187396-92-5 5-chloro-1-(2,4-dimethoxy-5-nitrophenyl)-1-pentanone 
• 33245-78-2 5-chloro-1-(2,4-dimethoxyphenyl)pentan-1-one 

Downstream Products

• 187397-00-8 N-[5-(5-chloropentanoyl)-2,4-dimethoxyphenyl]-4-trifluoromethylbenzenesulfonamide 
• 185376-80-1 N-[5-(5-Chloro-pentanoyl)-2,4-dimethoxy-phenyl]-benzenesulfonamide 
• 185376-97-0 N-{5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)pentanoyl]-2,4-dimethoxyphenyl}-4-trifluoromethylbenzenesulfonamide 

Relevant academic research and scientific papers

Some benzenesulfonamido-substituted valerophenones that are selective antagonists for the 5-HT(2C) receptor

Substituted benzenesulfonyl derivatives of m-aminovalerophenones bearing a 1,3,8-triazaspiro[4.5]decane-2,4-dione at the alkyl terminus are the first known, selective ligands for the 5-HT(2C) receptor. A brief structure-activity relationship of this series is outlined.