187480-23-5

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 187480-40-6 N'-methyl-N-(3-methylbenzyl)ethylenediamine 
• 77-92-9 citric acid 
• 123387-72-4 O-tert-butyl N-methyl-N-(2-oxoethyl)carbamate 
• 57561-39-4 methyl(2-hydroxyethyl)carbamic acid tert-butyl ester 

Downstream Products

• 187480-40-6 N'-methyl-N-(3-methylbenzyl)ethylenediamine 

Relevant academic research and scientific papers

(R)-5-bromo-N-(1-ethyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridinecarboxamide, process for producing the same and medicinal composition containing the same

This invention discloses a compound which is expressed by formula (I) below: STR1 or physiologically acceptable acid addition salts thereof. The claimed compound exhibits excellent antiemetic effect based on its potent serotonin S3 and dopamine

Efficient synthesis of (6R)-6-amino-1-methyl-4-(3-methylbenzyl)-hexahydro-1H-1,4-diazepine from methyl (2R)- and (2S)-1-benzyloxycarbonylaziridine-2-carboxylates

An efficient and practical method for the synthesis of (6R)-6-amino-1-methyl-4-(3-methylbenzyl)hexahydro-1H-1,4-diazepine 2, which serves as the amine part of DAT-582, a potent and selective 5-HT3 receptor antagonist, is described. The key inte