187655-56-7

Basic information

• Product Name: Tataramide B
• Synonyms: Tataramide B;(2R,3R)-rel-2,3-Dihydro-2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-5-[(1Z)-3-[[2-(4-hydroxyphenyl)ethyl]amino]-3-oxo-1-propen-1-yl]-7-methoxy-3-benzofurancarboxamide
• CAS NO: 187655-56-7
• Molecular Formula: C36H36N2O8
• Molecular Weight: 624.68
• Mol File: 187655-56-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 934.8±65.0 °C(Predicted)
• Appearance: /
• Density: 1.315±0.06 g/cm3(Predicted)
• PKA: 9.78±0.35(Predicted)
• CAS DataBase Reference: Tataramide B(CAS DataBase Reference)
• NIST Chemistry Reference: Tataramide B(187655-56-7)
• EPA Substance Registry System: Tataramide B(187655-56-7)

Safety Data

• Hazardous Substances Data: 187655-56-7(Hazardous Substances Data)

Upstream product

• 118799-80-7 (E)-methyl 3-<(2RS,3SR)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methoxycarbonyl-1-benzofuran-5-yl>-1-propenoate 
• 2309-07-1 Methyl ferulate 
• 118799-81-8 methyl (E)-3-<(2R*,3R*)-2,3-dihydro-7-methoxy-3-methoxycarbonyl-2-(3-methoxy-4-methoxymethoxyphenyl)-1-benzofuran-5-yl>propenoate 
• 66648-43-9 (E)-N-feruloyltyramine 
• 65646-26-6 (Z)-N-feruloyltyramine 
• 51-67-2 tyrosamine 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 

Relevant articles and documents

Comparative analysis of stilbene and benzofuran neolignan derivatives as acetylcholinesterase inhibitors with neuroprotective and anti-inflammatory activities

Stilbenes and benzofuran neolignans are important groups of plant phenolics therefore they play a significant role in plants and human health. The objective of this study was to investigate the structure-activity relationships of naturally occurring stilbene and benzofuran neolignan derivatives as acetylcholinesterase inhibitors. A series of these compounds were prepared and assessed for their inhibition on acetylcholinesterase activity. δ-Viniferin, pterostilbene trans-dehydrodimer, pallidol, grossamide, and boehmenan exerted acetylcholinesterase inhibitory potential. The several oligomeric compounds protected against cell damage resulting from t-BHP exposure and inhibited lipopolysaccharide/interferon-gamma (LPS/IFNγ)-induced NO production in vitro. Our findings highlight the great potential of pterostilbene trans-dehydrodimer, pallidol, and boehmenan as multifunctional nutraceuticals for management of neurodegenerative diseases.

TERMITE ANTIFEEDANT ACTIVITY IN XYLOPIA AETHIOPICA

A heaxne extract of xylopia aethiopica fruits and an aqueous methanol extract of the seeds were studied for termite antifeedant activity against workers of the subterranean termite, Reticullitermes speratus.The crude extract, at1percent exhibited strong antifeedant activity in a choice filter paper disk bioassay.Bioassay-directed fractionation led to the isolation and identification of six ent-kaurane diterpenes in the hexane extract.Feeding deterrent activity varied significantly with the structures when the compounds were tested at concentrations ranging from 5000 ppm (40 μg cm-2) to 100 ppm (0.824 μg cm-2). (-)-Kaur-16-en-19-oic acid had the strongest termite antifeedants activity among the ent-kauranes isolated.Two phenolic amides and four lignanamides were also isolated from the aqueous methanolic extract of seeds.E-3-(4-hydroxy-3-methoxyphenyl)-N-2-2-propenamide was more active than E-3 (3,4-dihydroxyphenyl)-N-2-2-propenamide, whilst grossamide and the new lignanamide, demethylgrossamide, as well as (-)-cannabisins B and D exhibited potent feeding deterrent activity at 5000 ppm.The identity of these compounds was established by spectroscopic analysis and synthesis.Two synthetic amides, E-3-(3,4-methylenedioxyphenyl)-N-2- propenamide and E-3-(3,4-methylenedioxyphenyl)-N-2--2-propenamide were also tested for antifeedant activity. - Keywords: xylopia aethiopica; Annonaceae; seeds; fruits; Reticullitermes speratus; Isoptera; antifeedants; ent-kaurane diterpenes; phenolic amides; lignanamides.