187665-54-9

Upstream product

• 187665-47-0 (2R,5R)-5-(1-chloromethylethenyl)-2-methylcyclohexanone 
• 187665-49-2 (3R,6R)-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-benzyloxypropylidene]-6-methylcyclohexanone 
• 187665-48-1 (2R,3R,6R)-3-[1-(chloromethyl)ethenyl]-2-[(R)-1-hydroxy-3-benzyloxypropyl]-6-methylcyclohexanone 
• 187665-51-6 (1R,3R,6R)-1-allyl-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-benzyloxypropylidene]-1-(methoxymethoxy)-6-methylcyclohexane 
• 187665-52-7 (1R,3R,6R)-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-benzyloxypropylidene]-1-(methoxymethoxy)-6-methylcyclohexane propanol 
• 187665-50-5 (1R,3R,6R)-1-allyl-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-benzyloxypropylidene]-6-methyl-1-cyclohexanol 
• 100-52-7 benzaldehyde 
• 19790-60-4 3-Benzyloxypropanal 
• 5524-05-0 (2R,5R)-5-isopropenyl-2-methylcyclohexanone 
• 187665-53-8 (1R,3R,6R)-3-[1-(chloromethyl)ethenyl]-2-[(E)-3-benzyloxypropylidene]-1-(methoxymethoxy)-6-methylcyclohexane propanal 

Relevant academic research and scientific papers

Efficient construction of 8-membered ring framework of vinigrol through SmI2-induced coupling cyclization

The 8-membered ring framework of vinigrol, a unique tricyclic diterpene isolated as a novel antihypertensive compound from a culture of Virgaria nigra, was efficiently synthesized employing an SmI2-induced intramolecular coupling. It is particularly noteworthy that the 8-membered carbocycle was cyclized in quantitative yields under non-high-dilution conditions.