187682-45-7

Upstream product

• 187682-33-3 methyl (1aS,8R,8aS,8bR)-1,1a,2,8,8a,8b-hexahydro-7-(benzyloxy)-8-(hydroxymethyl)-1-(tert-butyloxycarbonyl)azirino[2',3':3,4]pyrrolo[1,2-a]indole-5-carboxylate 
• 187682-43-5 methyl (1aS,8R,8aS,8bR)-1,1a,2,8,8a,8b-hexahydro-7-(benzyloxy)-8-[(acetyloxy)methyl]-1-(tert-butyloxycarbonyl)-8-formylazirino[2',3':3,4]pyrrolo[1,2-a]indole-5-carboxylate 
• 187682-39-9 methyl (1aS,8R,8aS,8bR)-1,1a,2,8,8a,8b-hexahydro-7-(benzyloxy)-1-(tert-butyloxycarbonyl)-8-formyl-8-(hydroxymethyl)azirino[2',3':3,4]pyrrolo[1,2-a]indole-5-carboxylate 
• 187682-40-2 C₂₆H₂₈N₂O₆ 
• 187682-44-6 methyl (1aS,8R,8aS,8bS)-1,1a,2,8,8a,8b-hexahydro-8-[(acetyloxy)methyl]-7-(benzyloxy)-1-(tert-butyloxycarbonyl)-8-formylazirino[2',3':3,4]pyrrolo[1,2-a]indole-5-carboxylate 3-oxide 

Relevant academic research and scientific papers

Chiral aziridinyl radicals: An application to the synthesis of the core nucleus of FR-900482

An asymmetric route to the core nucleus of the antitumor agent FR-900482 utilizes the cyclization of an aziridinyl radical into a functionalized indole nucleus. The route employs a selective Polonovski reaction and the Hootele-Dmitrienko rearrangement to install two oxygen atoms.