187840-93-3Relevant academic research and scientific papers
Synthesis and biological activity of β-glucuronyl carbamate-based prodrugs of paclitaxel as potential candidates for ADEPT
De Bont, Dries B. A.,Leenders, Ruben G. G.,Haisma, Hidde J.,Van Der Meulen-Muileman, Ida,Scheeren, Hans W.
, p. 405 - 414 (1997)
The syntheses of prodrugs of paclitaxel which can be used in ADEPT in order to target paclitaxel towards tumor cells, are described. The prodrugs 1 and 2a,b consist of a spacer molecule connected via a carbamate linkage to a β-glucuronic acid. The spacer
