
Bioorganic and Medicinal Chemistry p. 405 - 414 (1997)
Update date:2022-08-05
Topics:
De Bont, Dries B. A.
Leenders, Ruben G. G.
Haisma, Hidde J.
Van Der Meulen-Muileman, Ida
Scheeren, Hans W.
The syntheses of prodrugs of paclitaxel which can be used in ADEPT in order to target paclitaxel towards tumor cells, are described. The prodrugs 1 and 2a,b consist of a spacer molecule connected via a carbamate linkage to a β-glucuronic acid. The spacer
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