187844-52-6Relevant academic research and scientific papers
Convenient synthesis of 2,2-disubstituted-2,3-dihydro-1,4-benzodioxins from 2-substituted-2-hydroxy-2,3-dihydro-1,4-benzodioxins
Thiery, Valerie,Coudert, Gerard,Guillaumet, Gerald
, p. 2061 - 2074 (2007/10/03)
Convenient syntheses of relatively rare 2,2-disubstituted-2,3-dihydro-1,4-benzodioxins from 2-substituted-2-hydroxy-2,3-dihydro-1,4-benzodioxins, as key synthetic intermediates, are reported. These new synthetic approaches require Lewis acid BF3-Et2O mediated nucleophilic substitution reaction or cyclization of suitable hydroxyphenols.
