187869-29-0

Basic information

• Product Name: 2,2-bis(phenylthio)-N-[o-(prop-2-enyl)phenyl]acetamide
• CAS NO: 187869-29-0
• Molecular Weight: 391.558
• Mol File: 187869-29-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-bis(phenylthio)-N-[o-(prop-2-enyl)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-bis(phenylthio)-N-[o-(prop-2-enyl)phenyl]acetamide(187869-29-0)
• EPA Substance Registry System: 2,2-bis(phenylthio)-N-[o-(prop-2-enyl)phenyl]acetamide(187869-29-0)

Safety Data

• Hazardous Substances Data: 187869-29-0(Hazardous Substances Data)

Upstream product

• 32704-22-6 2-allyl-phenylamine 
• 1914-64-3 Bisacetic acid 

Downstream Products

• 187869-69-8 3-Benzenesulfinyl-1-(4-methoxy-benzyl)-3,4,5,6-tetrahydro-1H-benzo[b]azocin-2-one 
• 187869-35-8 3,4,5,6-tetrahydro-1-(p-methoxybenzyl)-3-phenylthio-1-benzazocin-2(1H)-one 
• 187869-64-3 3,4,5,6-tetrahydro-1-(p-methoxybenzyl)-1-benzazocin-2(1H)-one 
• 22246-75-9 3,4,5,6-tetrahydro-1-benzazocin-2(1H)-one 
• 68267-69-6 N-acetyl-2-allylaniline 

Relevant articles and documents

Synthesis of tetrahydro-1-benzazocin-2(1H)-ones using 8-endo-trig radical cyclization of 2,2-bis-(phenylthio)-at-[o-(prop-2-enyl)-phenyl]acetamides

The effects of N-substituents upon the 8-endo-trig radical cyclization of 2,2-bis(phenylthio)-N-[o-(prop-2-enyl)phenyl]acetamides (4) were examined. The N-(p-methoxybenzyl) (4a) and N-tosyl derivatives (4b), when treated with tributyltin hydride in the presence of a small amount of azoisobutyronitrile, gave regioselectively the corresponding 3,4,5,6-tetrahydro-3-phenylthio-1-benzazocin2(1H)-ones (5a,b) (8-endo cyclization products) in 40 and 47% yields, respectively, while the N-unsubstituted derivative (4c) afforded the reduction products (6c) and (8) as the major products. Some chemical transformation reactions of 5a are also described.