187973-60-0

Basic information

• Product Name: 6-iodopyridazin-3-amine
• Synonyms: 3-Amino-6-iodopyridazine;6-Iodopyridazin-3-amine, 3-Amino-6-iodo-1,2-diazine
• CAS NO: 187973-60-0
• Molecular Formula: C₄H₄IN₃
• Molecular Weight: 220.99913
• Mol File: 187973-60-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 399.6 °C at 760 mmHg
• Flash Point: 195.5 °C
• Appearance: /
• Density: 2.204
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.24±0.10(Predicted)
• CAS DataBase Reference: 6-iodopyridazin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-iodopyridazin-3-amine(187973-60-0)
• EPA Substance Registry System: 6-iodopyridazin-3-amine(187973-60-0)

Safety Data

• Hazardous Substances Data: 187973-60-0(Hazardous Substances Data)

Usage

General Description

6-iodopyridazin-3-amine is a chemical compound with the molecular formula C4H3IN4. It is a derivative of pyridazine and contains an iodine atom and an amine group. 6-iodopyridazin-3-amine has potential pharmacological and medicinal applications due to its structural features and reactivity. It can also be used as a building block in organic synthesis to create more complex molecules. Its properties and uses make it a valuable compound in the field of chemistry and pharmaceutical research.

Upstream product

• 5469-69-2 6-chloro-pyridazin-3-ylamine 

Downstream Products

• 188692-52-6 2-(4-Cyclohexyl-phenyl)-6-iodo-imidazo[1,2-b]pyridazine 
• 188692-49-1 2-(4-tert-Butyl-phenyl)-6-iodo-imidazo[1,2-b]pyridazine 
• 188692-55-9 2-([1,1'-biphenyl]-4-yl)-6-iodoimidazo[1,2-b]pyridazine 
• 188692-46-8 6-Iodo-2-phenyl-imidazo[1,2-b]pyridazine 
• 188692-58-2 6-Iodo-2-(4-iodo-phenyl)-imidazo[1,2-b]pyridazine 
• 1220909-58-9 C₁₄H₁₃IN₄ 
• 1220909-62-5 C₁₂H₇IN₄O₂ 
• 1206487-35-5 4,6-dibromopyridazin-3-amine 
• 66346-91-6 6-morpholinopyridazin-3-amine 
• 1439400-51-7 N-(6-iodopyridazin-3-yl)-2-phenylacetamide 
• 1005785-69-2 ethyl (6-iodoimidazo[1,2-b]pyridazin-2-yl)carbamate 
• 1005787-84-7 tert-butyl N-[6-iodoimidazo[1,2-b]pyridazin-2-yl]carbamate 

Relevant articles and documents

Macrocyclic glutaminase GLS1 inhibitor or pharmaceutically acceptable salt thereof and preparation method and application thereof

The invention relates to the field of biological medicine, in particular to a series of macrocyclic glutaminase inhibitors, a synthesis method and medical application thereof, and particularly relatesto prevention or treatment of glutaminase related diseases. Meanwhile, the inventor performs a series of in-vitro anti-tumor activity evaluation on the synthesized compounds, and particularly, most of the compounds have good inhibitory activity on cancer cells.

PYRROLIDINO HETEROCYCLES

The invention relates to compounds of formula I wherein A1, A2, A3, B, R1, R2, R3 and R4 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit PDE10A and can be used as medicaments.

IMIDAZOLE DERIVATIVES

The present invention relates to compounds of formula (I), wherein A, B, R1 and R2 are as defined herein before.