187975-82-2Relevant academic research and scientific papers
Synthesis of β-hydroxyphosphonates by iron-catalyzed oxidative addition of phosphonyl radicals to alkenes
Taniguchi, Tsuyoshi,Idota, Atsushi,Yokoyama, Shin'Ichi,Ishibashi, Hiroyuki
experimental part, p. 4768 - 4770 (2011/10/02)
Phosphorohydrazidates have been shown to work as radical precursors by iron-catalyzed aerobic oxidation to generate corresponding phosphonyl radicals. Generated radicals cause intermolecular addition to various alkenes in the presence of molecular oxygen
A new entry to β-hydroxyphosphonates: The SmI2-mediated reaction of diethyl iodomethylphosphonate with carbonyl compounds
Orsini, Fulvia,Caselli, Alessandro
, p. 7255 - 7257 (2007/10/03)
In the presence of samarium iodide α-halophosphonates react with aliphatic carbonyl compounds (aldehydes and ketones) to afford β-hydroxyphosphonates in fairly good yields under neutral and mild conditions. Lower yields are obtained with aromatic carbonyl compounds.
A convenient (E)-stereoselective synthesis of alkenylphosphonates
Truel, Isabelle,Mohamed-Hachi, Abdourahman,About-Jaudet, Elie,Collignon, Noel
, p. 297 - 302 (2007/10/03)
Diethyl (E)-alkenylphosphonates have been prepared stereoselectively by dehydration of the corresponding β-hydroxyphosphonates using DCC/CuCl2 in refluxing toluene. Starting β-hydroxyphosphonates were obtained in high yield from diethyl methylphosphonate.
