187993-26-6 Usage
Uses
Dihydro-3-[(3-Methoxyphenyl)Methyl]-2(3H)-furanone is used in the pharmaceutical industry for the preparation of 4,5-diaryloxazole derivatives. These derivatives are known to act as prostaglandin I2 antagonists, which play a crucial role in various physiological processes and have potential therapeutic applications.
Used in Pharmaceutical Industry:
Dihydro-3-[(3-Methoxyphenyl)Methyl]-2(3H)-furanone is used as a key intermediate in the synthesis of 4,5-diaryloxazole derivatives for their application as prostaglandin I2 antagonists. The compound's unique structure allows for the development of new drugs that can modulate the activity of prostaglandins, which are involved in inflammation, pain, and other physiological processes. By acting as antagonists, these derivatives can potentially be used to treat conditions where prostaglandin I2 activity is detrimental or needs to be controlled.
Check Digit Verification of cas no
The CAS Registry Mumber 187993-26-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,9,9 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 187993-26:
(8*1)+(7*8)+(6*7)+(5*9)+(4*9)+(3*3)+(2*2)+(1*6)=206
206 % 10 = 6
So 187993-26-6 is a valid CAS Registry Number.
187993-26-6Relevant academic research and scientific papers
Copper(II)-Promoted Cyclization/Difunctionalization of Allenols and Allenylsulfonamides: Synthesis of Heterocycle-Functionalized Vinyl Carboxylate Esters
Casavant, Barbara J.,Khoder, Zainab M.,Berhane, Ilyas A.,Chemler, Sherry R.
supporting information, p. 5958 - 5961 (2016/01/09)
A unique method to affect intramolecular aminooxygenation and dioxygenation of allenols and allenylsulfonamides is described. These operationally simple reactions occur under neutral or basic conditions where copper(II) carboxylates serve as reaction promoter, oxidant, and carboxylate source. Moderate to high yields of heterocycle-functionalized vinyl carboxylate esters are formed with moderate to high levels of diastereoselectivity. Such vinyl carboxylate esters could serve as precursors to α-amino and α-oxy ketones and derivatives thereof.
4,5-dipheny-oxazole derivatives and their use as platelet aggregation inhibitors
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Example 1(2), (2010/02/05)
Heterocyclic compounds of the formula: ???whereinR1 is carboxy or esterified carboxy,R2 is phenyl or (C1-C6)alkylphenyl,R3 is phenyl or (C1-C6)alkylphenyl,R4 is hydrog
