18807-69-7Relevant academic research and scientific papers
Novel pseudo[2]rotaxanes constructed by the self-assembly of dibenzyl tetramethylene bis-carbamate derivatives and per-ethylated pillar[5]arene
Xiong, Shuhan,Zhang, Xiaoning,Meng, Lu-Bo,Jiang, Juli,Lin, Chen,Wang, Leyong
, p. 6504 - 6507 (2015)
Novel neutral guest molecules, G1-G7, are studied for their host-guest complexation with per-ethylated pillar[5]arene (EtP[5]A). Among them, G1 and G7, dibenzyl tetramethylene bis-carbamate derivatives, are found to afford a novel stable pseudo[2]rotaxane
Syntheses of [13C,15N]-Labeled Polyamines
Hara, Takeshi,Xu, Yong Ji,Sasaki, Hitomi,Niitu, Masaru,Samejima, Keijiro
, p. 1005 - 1012 (2007/10/03)
[1,4-13C2, 1,4-15N2]butanediamine (1), a key compound in the syntheses of [5,8-13C2, 1,4,8-15N3]spermidine (2) and [5,8-13C2, 1,4,8,12-15N4]spermine (3), has been prepared as part of a 6-step process from 1,2-dibromoethane using potassium [13C]cyanide and potassium [15N]phthalimide. In the course of the syntheses, it was found that 1,4-dibromobutane was generated from tetrahydrofuran when bromination using triphenylphosphine and tetrabromomethane took place. A high-yield preparation of monobenzyloxycarbonyl (Z) derivative of 1, a precursor for 2, was obtained using a water-soluble Z reagent, Z-DSP, in a two-phase system of alkaline solution and chloroform. All the steps for 1, 2, and 3, were aimed at minimizing the loss of stable isotopes.
Practical, convergent total synthesis of polyamine amide spider toxin NSTX-3
Blagbrough, Ian S.,Moya, Eduardo,Walford, Steven P.
, p. 551 - 554 (2007/10/02)
A practical, total synthesis of polyamine amide spider toxin NSTX-3, a potent glutamate receptor antagonist with potential as a neuroprotective agent, is reported. The unsymmetrical polyamine moiety was built by a conjugate addition to afford putreanine and regioselective acylation of L-asparaginyl-cadaverine.
SYNTHESIS OF N-(1-URACILYLALKYL)POLYMETHYLENEDIAMINES
Lulle, I. Zh.,Kagan, T. I.,Paegle, R. A.,Lidak, M. Yu.
, p. 1224 - 1227 (2007/10/02)
The alkylation of polymethylenediamines with 2-(1-uracilyl)ethyl bromide and 3-(1-uracilyl)propyl bromide yields the corresponding N-(1-uracilylalkyl)polymethylendiamines.
