188183-27-9

Basic information

• Product Name: (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-cyanopropanoate
• Synonyms: (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-cyanopropanoate
• CAS NO: 188183-27-9
• Molecular Weight: 478.696
• Mol File: 188183-27-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-cyanopropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-cyanopropanoate(188183-27-9)
• EPA Substance Registry System: (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-cyanopropanoate(188183-27-9)

Safety Data

• Hazardous Substances Data: 188183-27-9(Hazardous Substances Data)

Upstream product

• 4158-25-2 2-cyanopropanoyl chloride 
• 96303-88-7 (-)-10-dicyclohexylsulfamoyl-D-isoborneol 

Downstream Products

• 143100-05-4 (2S)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-cyano-2-methyl-3-phenylpropanoate 
• 143100-04-3 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-cyano-2-methyl-3-phenylpropanoate 
• 154520-13-5 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-cyano-2-methylbutanoate 
• 173914-46-0 (2R)-(1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-amino-2-aminomethylpropanoate 
• 219567-02-9 (R)-2-Cyano-3-hydroxy-2-methyl-propionic acid (1S,2R,4R)-1-[(dicyclohexylsulfamoyl)-methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 154520-16-8 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-cyano-2,3-dimethylbutanoate 
• 144631-58-3 (2S)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-(aminomethyl)-2-methyl-3-phenylpropanoate 
• 144631-56-1 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-(aminomethyl)-2-methyl-3-phenylpropanoate 

Relevant articles and documents

Stereoselective Amination of Chiral Enolates: Synthesis of enantiomerically pure α,β-Diamino Acids, Chiral Key Compounds in the Synthesis of Conformationally Constrained Peptido- and Non-peptidomimetics

This work describes an efficient synthesis of enantiomerically pure (R)-2-aminomethylalanine, (R)-2-aminomethylnorvaline, (R)-2-aminomethylvaline, (R)-2-aminomethylleucine and (R)-2-aminomethylphenylalanine by electrophilic amination of chiral 2-cyanoeste

Asymmetric Synthesis of β-Lactams. Highly Diastereoselective Alkylation of Chiral 2-Cyano Esters

Enolates derived from 10-(dicyclohexylsulfamoyl)isobornyl 2-substituted-2-cyanoacetates were alkylated with very good yield and high diastereoselectivity.The reduction of the resulting reaction products and subsequent cyclization of the β-amino acids led