188255-39-2

Upstream product

• 18075-41-7 2-allyl-3-hydroxy-4-methoxybenzaldehyde 
• 621-59-0 isovanillin 
• 106-95-6 allyl bromide 
• 75-26-3 isopropyl bromide 
• 75-30-9 2-iodo-propane 
• 18075-40-6 O-allylisovanillin 

Downstream Products

• 188255-54-1 2'-Allyl-3'-isopropoxy-3'',4',4''-trimethoxybenzophenone 
• 188255-51-8 (2-allyl-3-isopropoxy-4-methoxyphenyl)(phenyl)methanone 
• 267898-09-9 (2-Allyl-3-isopropoxy-4-methoxyphenyl)(phenyl)methanol 
• 267898-10-2 (2'-Allyl-3'-isopropoxy-4'-methoxyphenyl)(1''-naphthyl)methanol 
• 267898-11-3 (2'-Allyl-3'-isopropoxy-4'-methoxyphenyl)(3'',4''-dimethoxyphenyl)methanol 
• 469898-64-4 3-isopropoxy-4-methoxy-1-(1'-hydroxyethyl)-2-(prop-2'-enyl)benzene 
• 691354-56-0 N-[1-(2-Allyl-3-isopropoxy-4-methoxy-phenyl)-meth-(E)-ylidene]-4-methyl-benzenesulfonamide 
• 634616-23-2 (2-allyl-3-isopropoxy-4-methoxyphenyl)methanol 
• 841301-96-0 1-(2-allyl-3-isoproxy-4-methoxyphenyl)-3-buten-1-ol 
• 825633-47-4 (1R)-N-[(2-allyl-3-isopropoxy-4-methoxyphenyl)methyl]-(1-phenylethyl)amine 
• 767290-03-9 2-allyl-3-isopropoxy-4-methoxyphenol 
• 942592-40-7 N-allyl-N-(2-allyl-3-isopropoxy-4-methoxybenzyl)acetamide 
• 942592-41-8 tert-butyl allyl(2-allyl-3-isopropoxy-4-methoxybenzyl)carbamate 
• 817629-07-5 N-allyl-N-(2-allyl-3-isopropoxy-4-methoxybenzyl)phenylmethanesulfonamide 

Relevant academic research and scientific papers

CuI Mediated One-Pot Cycloacetalization/Ketalization of o-Carbonyl Allylbenzenes: Synthesis of Benzobicyclo[3.2.1]octane Core

CuI/DMSO-mediated intramolecular cycloacetalization/ketalization of o-carbonyl allylbenzenes has been achieved for constructing [6,6,5]-tricycles having a ketal motif in good yields. The expeditious one-step route provides a three C-O bond formation. The key products with the structural framework of a benzofused dioxabicyclo[3.2.1]octane core have been confirmed by X-ray crystallographic analysis. Synthesis of dihydroisocoumarin has been studied.

Synthesis of dihydrobenzoimidazo[2,1-a]isoquinolines

A one-pot protocol toward several substituted 5,6-dihydrobenzo[4,5] imidazo[2,1-a]isoquinolines 1 starting with 2-allylbenzaldehydes 2 was described. The process was carried out the one-pot condensation/hydroamination reaction of substituted 2-allylbenzaldehydes 2 with 1,2-diaminobenzenes 3 in refluxing toluene in good yields. Skeleton 2 was prepared via one-pot ortho-metalative PhBCl2-mediated double alkylation of hydroxybenzaldehyde 4 with LDA in moderate yields.

Claisen rearrangement/Baylis-Hillman reaction/ring-closing metathesis as bases for the construction of substituted cyanonaphthalenes

The present paper described how to establish a novel approach for various alkoxycyanonaphthalenes. It was started from isovanillin, and based on the Claisen rearrangement, O-alkylation, the Baylis-Hillman reaction, and ring-closing metathesis in sequence

Synthesis of dibenzo-fused 10-membered cyclic ethers from isovanillin Via ring-closing metathesis

A synthesis of substituted dibenzo-fused 10-membered cyclic ethers is described. 2-Allylbenzyl alcohols and 2-allylphenols derived from isovanillin were coupled by the Mitsunobu reaction to construct intramolecular dienes with ether linkage. The resulting

The synthesis of R-3-alkoxy-1-(1′-hydroxyethyl)-4-methoxy-2-(1″-propenyl)benzenes utilizing Corey-Bakshi-Shibata asymmetric reductions

Pyrolysis of the 3-O-allyl derivative 7 of isovanillin followed by alkylation of the derived allylphenol 8 afforded a series of benzaldehyde derivatives 9-11 each of which was transformed by initial treatment with methylmagnesium bromide followed by oxida

Towards the synthesis of chiral isochromanquinones. The use of Corey-Bakshi-Shibata reductions

(1R,3R,4S)-3,4-Dihydro-4-hydroxy-6-methoxy-1,3-dimethylisochroman-5,8-dione has been synthesized in 65% ee from (1R,3R,4S)-5-benzyloxy-3,4-dihydro-4-hydroxy-6-methoxy-1,3-dimethylisochroman by catalytic hydrogenolysis followed by Fremy's salt oxidation of

A novel method for the synthesis of substituted naphthalenes and phenanthrenes

A new method for the synthesis of substituted naphthalenes and phenanthrenes was discussed. A formal synthesis of tanshinone I was also studied. Natural products that contain a naphthalene or phenanthrene nucleus often exhibit biological activity, which makes them attractive targets in organic synthesis. The results showed that the reaction can be proceed through at least two different pathways.

A novel synthesis subtituted naphthalenes

Irradiation of 2-allylated acylbenzenes in DMF in the presence of potassium tert-butoxice constitutes a novel synthesis of substituted naphthalenes, including arylnaphthalenes. Typical examples including the conversions (1) → (2), (8) → (11) and (15) → (16).