188263-82-3

Basic information

• Product Name: Silane, (1,1-dimethylethyl)[(3-methyl-2-butenyl)oxy]diphenyl-
• CAS NO: 188263-82-3
• Molecular Formula: C21H28OSi
• Molecular Weight: 324.538
• Mol File: 188263-82-3.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Silane, (1,1-dimethylethyl)[(3-methyl-2-butenyl)oxy]diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1,1-dimethylethyl)[(3-methyl-2-butenyl)oxy]diphenyl-(188263-82-3)
• EPA Substance Registry System: Silane, (1,1-dimethylethyl)[(3-methyl-2-butenyl)oxy]diphenyl-(188263-82-3)

Safety Data

• Hazardous Substances Data: 188263-82-3(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 556-82-1 3-methyl-2-buten-1-ol 
• 177606-52-9 tert-butyl((3-methylbut-3-en-1-yl)oxy)diphenylsilane 

Downstream Products

• 189437-81-8 (E)-4-(tert-butyldiphenylsilanyloxy)-2-methyl-but-2-en-1-ol 
• 1188357-33-6 N-(benzyloxy)-4-(tert-butyldiphenylsilyloxy)-2,2-dimethylbutanimidoyl cyanide 
• 1434774-80-7 C₃₁H₄₈O₄Si₂ 
• 1434774-76-1 ethyl (E)-6-(tert-butyldiphenylsilyloxy)-3-hydroxy-4-methylhex-4-enoate 
• 136022-54-3 1-(tert-butyldiphenylsiloxy)-3-methyl-2-butanone 
• 188263-80-1 tert-Butyl-diphenyl-((2E,4E)-(R)-3,7,11-trimethyl-dodeca-2,4,10-trienyloxy)-silane 
• 189438-06-0 (2E,6E)-1-(tert-Butyl-diphenyl-silanyloxy)-3,7,11-trimethyl-dodeca-2,6,10-trien-4-ol 
• 189437-82-9 (E)-[(4-bromo-3-methylbut-2-ene-1-yl)oxy](t-butyl)diphenylsilane 
• 151409-23-3 tert-butyldiphenyl {[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy}silane 

Relevant articles and documents

Exploiting the Synthetic Potential of Sesquiterpene Cyclases for Generating Unnatural Terpenoids

The substrate flexibility of eight purified sesquiterpene cyclases was evaluated using six new heteroatom-modified farnesyl pyrophosphates, and the formation of six new heteroatom-modified macrocyclic and tricyclic sesquiterpenoids is described. GC-O analysis revealed that tricyclic tetrahydrofuran exhibits an ethereal, peppery, and camphor-like olfactoric scent.

Stereoselective alkene isomerization over one position

Although controlling both the position of the double bond and E:Z selectivity in alkene isomerization is difficult, 1 is a very efficient catalyst for selective mono-isomerization of a variety of multifunctional alkenes to afford >99.5% E-products. Many reactions are complete within 10 min at room temperature. Even sensitive enols and enamides susceptible to further reaction can be generated. Catalyst loadings in the 0.01-0.1 mol% range can be employed. E-to-Z isomerization of the product from diallyl ether was only -6 times as fast as its formation, showing the extremely high kinetic selectivity of 1.

IspG converts an epoxide substrate analogue to (E)-4-hydroxy-3-methylbut-2- enyl diphosphate: Implications for IspG catalysis in isoprenoid biosynthesis

(Chemical Equation Presented) IspG is an intriguing enzyme in bacteria, parasite, and plant isoprenoid biosynthesis, and its catalytic mechanism remains elusive. We report here the synthesis of (2R,3R)-4-hydroxy-3-methyl-2,3- epoxybutanyl diphosphate (Epoxy-HMBPP), a proposed intermediate in one of the frequently cited mechanistic models. We have also demonstrated that this epoxide analogue is a catalytically competent IspG substrate. This study represents the first mechanistic study of this important enzyme.