188299-19-6Relevant articles and documents
Guanidinium ylide mediated aziridination: Identification of a spiro imidazolidine-oxazolidine intermediate
Disadee, Wannaporn,Ishikawa, Tsutomu,Kawahata, Masatoshi,Yamaguchi, Kentaro
, p. 6600 - 6603 (2006)
We successfully isolated a spiro imidazolidine-oxazolidine intermediate in the reaction of guanidinium ylide mediated aziridination using α-bromocinnamaldehyde. X-ray crystallographic analysis unambiguously revealed that the stereogenic centers of the spi
Pentanidium-catalyzed enantioselective phase-transfer conjugate addition reactions
Ma, Ting,Fu, Xiao,Kee, Choon Wee,Zong, Lili,Pan, Yuanhang,Huang, Kuo-Wei,Tan, Choon-Hong
supporting information; experimental part, p. 2828 - 2831 (2011/04/22)
A new chiral entity, pentanidium, has been shown to be an excellent chiral phase-transfer catalyst. The enantioselective Michael addition reactions of tert-butyl glycinate-benzophenone Schiff base with various α,β- unsaturated acceptors provide adducts with high enantioselectivities. A successful gram-scale experiment at a low catalyst loading of 0.05 mol % indicates the potential for practical applications of this methodology. Phosphoglycine ester analogues can also be utilized as the Michael donor, affording enantioenriched α-aminophosphonic acid derivatives and phosphonic analogues of (S)-proline.
Simple preparation of chiral 1,3-dimethyl-2-iminoimidazolidines (monocyclic guanidines) and applications to asymmetric alkylative esterification
Isobe, Toshio,Fukuda, Keiko,Ishikawa, Tsutomu
, p. 1729 - 1735 (2007/10/03)
New chiral 1,3-dimethyl-2-iminoimidazolidines (monocyclic guanidines) were simply prepared by the action of primary amines on 2-chloro-1,3- dimethylimidazolinium chlorides, derived from the corresponding urea, in high yields. Modest asymmetric induction i
