188345-17-7

Upstream product

• 188345-22-4 2-pyridin-4-yl-1-(3-trifluoromethyl-phenyl)-ethanone 
• 85475-10-1 4-(2-chloroacetyl)piperidine-1-carboxylic acid benzyl ester 
• 502639-28-3 4-(3-pyridin-4-yl-acryloyl)-piperidine-1-carboxylic acid benzyl ester 
• 454-89-7 3-Trifluoromethylbenzaldehyde 

Downstream Products

• 188345-18-8 5-(1-benzyloxycarbonyl-4-piperidinyl)-3-(pyridin-4-yl)-2-(3-trifluoromethylphenyl)-pyrrole 
• 271247-40-6 3-(3-trifluoromethylphenyl)-4-(pyridin-4-yl)-6-(N-carbobenzoxypiperidin-4-yl)pyridazine 

Relevant academic research and scientific papers

2-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE

The present invention addresses 2-substituted aryl pyrroles, as well as compositions containing such compounds and methods of treatment. Cytokine mediated diseases refers to diseases or conditions in which excessive or unregulated production or activity o

Compounds having cytokine inhibitory activity

There are disclosed compounds of formula (I) and pharmaceutically acceptable salts thereof which exhibit utility for the treatment of cytokine mediated diseases such as arthritis.

2-substituted aryl pyrroles, compositions containing such compounds and methods of use

The present invention addresses 2-substituted aryl pyrroles, as well as compositions containing such compounds and methods of treatment. Cytokine mediated diseases refers to diseases or conditions in which excessive or unregulated production or activity o