188358-98-7Relevant academic research and scientific papers
Hydroxylamine-Derived Reagent as a Dual Oxidant and Amino Group Donor for the Iron-Catalyzed Preparation of Unprotected Sulfinamides from Thiols
Chatterjee, Sayanti,Makai, Szabolcs,Morandi, Bill
supporting information, p. 758 - 765 (2020/11/30)
An iron catalyzed reaction for the selective transformation of thiols (-SH) to sulfinamides (-SONH2) by a direct transfer of -O and free -NH2 groups has been developed. The reaction operates under mild conditions using a bench stable hydroxylamine derived reagent, exhibits broad functional group tolerance, is scalable and proceeds without the use of any precious metal catalyst or additional oxidant. This novel, practical reaction leads to the formation of two distinct new bonds (S=O and S?N) in a single step to chemoselectively form valuable, unprotected sulfinamide products. Preliminary mechanistic studies implicate the role of the alcoholic solvent as an oxygen atom donor.
Synthesis of dihydroindolizines for potential photoinduced work function alteration
Bartucci, Matthew A.,Wierzbicki, Patrycja M.,Gwengo, Chengeto,Shajan, Sunny,Hussain, Syed H.,Ciszek, Jacob W.
, p. 6839 - 6842 (2011/03/18)
Seeking to immobilize photochromophores on metallic surfaces, we have synthesized four molecules which contain both a photoresponsive dihydroindolizine (DHI) core and a sulfur containing moiety, which allow for their assembly onto gold substrates. Sonogashira, Suzuki, or Ullmann couplings are employed to generate pyridines with pendant thioacetates (or disulfides). The pyridines are condensed with spiro[2-cyclopropene-1, 9′-[9H]fluorene]- 2, 3-dimethyl ester affording the targeted DHIs.
1-Methylpyridinium-4-(4-phenylmethanethiosulfonate) iodide, MTS-MPP+, a novel scanning cysteine accessibility method (SCAM) reagent for monoamine transporter studies
Gallardo-Godoy, Alejandra,Torres-Altoro, Melissa I.,White, Kellie J.,Barker, Eric L.,Nichols, David E.
, p. 305 - 311 (2008/02/04)
A novel substituted cysteine accessibility method (SCAM) reagent was developed for monoamine uptake transporters. The new reagent, MTS-MPP+, was a derivative of the neurotoxin and transporter substrate MPP+. MTS-MPP+ label
Nucleophilic properties of thiourea towards aromatic halides
Combellas,Dellerue,Mathey,Thiebault
, p. 539 - 542 (2007/10/03)
Arylsulfides (and diaryldisulfides obtained spontaneously by oxidation of the arylsulfides during the work-up) and diarylsulfides can be obtained by substituting aryl radicals by the thiourea onion in liquid ammonia under an electrochemical inducement.
