188569-97-3Relevant articles and documents
Radical cyclization in heterocycle synthesis. Part 10: A concise synthesis of (-)-kainic acid via sulfanyl radical addition-cyclization-elimination reaction
Miyata, Okiko,Ozawa, Yoshiki,Ninomiya, Ichiya,Naito, Takeaki
, p. 6199 - 6207 (2007/10/03)
Sulfanyl radical addition-cyclization-elimination of diallylamines in the presence of thiophenol and AIBN gave the 2,3,4-trisubstituted pyrrolidine in high yield. This reaction was extended to a radical cyclization using a catalytic amount of thiophenol. A successful application was demonstrated by the asymmetric synthesis of (-)-kainic acid. (C) 2000 Elsevier Science Ltd.
An Enantioselective Synthesis of (-)-α-Kainic Acid via Thiyl Radical Addition-Cyclization-Elimination Reaction
Miyata, Okiko,Ozawa, Yoshiki,Ninomiya, Ichiya,Naito, Takeaki
, p. 275 - 276 (2007/10/03)
An enantioselective synthesis of (-)-α-kainic acid has been achieved via the route involving thiyl radical addition-cyclization-elimination reaction.