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1886-26-6

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1886-26-6 Usage

Description

Norfenfluramine is a chemical compound belonging to the class of amphetamine derivatives, which was formerly used as an anorectic agent for the treatment of obesity. It functions by increasing the release of serotonin, a neurotransmitter that regulates mood and appetite, in the brain. However, due to its potential for causing pulmonary hypertension and valvular heart disease, the drug was withdrawn from the market in the 1990s. It has also been classified as a Schedule IV controlled substance due to its potential for abuse and addiction. Norfenfluramine is no longer available for medical use and is considered a banned substance in many countries.

Uses

Used in Pharmaceutical Industry:
Norfenfluramine was used as an anorectic agent for the treatment of obesity. It was utilized for its ability to increase the release of serotonin in the brain, which helps regulate mood and appetite, thereby aiding in weight loss management.
However, due to the associated health risks and regulatory restrictions, Norfenfluramine is no longer used in the pharmaceutical industry for these purposes.

Check Digit Verification of cas no

The CAS Registry Mumber 1886-26-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,8 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1886-26:
(6*1)+(5*8)+(4*8)+(3*6)+(2*2)+(1*6)=106
106 % 10 = 6
So 1886-26-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3

1886-26-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Phenethylamine, .α.-methyl-m-trifluoromethyl-

1.2 Other means of identification

Product number -
Other names 1-(3-trifluoromethylphenyl)-2-amino propane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1886-26-6 SDS

1886-26-6Relevant articles and documents

Hybrid Organo- and Biocatalytic Process for the Asymmetric Transformation of Alcohols into Amines in Aqueous Medium

Liardo, Elisa,Ríos-Lombardía, Nicolás,Morís, Francisco,Rebolledo, Francisca,González-Sabín, Javier

, p. 4768 - 4774 (2017/07/24)

A hybrid organo- and biocatalytic system for the asymmetric conversion of racemic alcohols into amines was developed. Combining an organocatalyst, AZADO, an oxidant, NaOCl, and an enzyme, ω-transaminase, we implemented a one-pot oxidation-transamination sequential process in aqueous medium. The method showed broad substrate scope and was successfully applied to conventional secondary alcohols and sterically hindered β-substituted cycloalkanols, where a highly stereoselective dynamic asymmetric bioamination enabled us to set up both contiguous stereocenters with very high enantio- and diastereomeric ratio (>90% yield, >99% ee, and up to 49:1 dr).

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