188624-24-0

Upstream product

• 15017-52-4 4-(bromomethyl)-1-fluoro-2-nitrobenzene 
• 20367-99-1 ethyl 2-(acetylamino)-2-(ethoxycarbonyl)-3-(4'-fluoro-3'-nitrophenyl)propanoate 
• 67-56-1 methanol 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 178744-40-6 (S)-2-[(R)-2-tert-Butoxycarbonylamino-2-(4-hydroxy-phenyl)-acetylamino]-3-(4-fluoro-3-nitro-phenyl)-propionic acid methyl ester 
• 199486-36-7 (11R,14S)-11-(4-Hydroxy-phenyl)-9,12-dioxo-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]henicosa-1⁽¹⁹⁾,3⁽²¹⁾,4,6,16⁽²⁰⁾,17-hexaene-14-carboxylic acid 
• 199486-35-6 (3S)-3-(4-fluoro-3-nitrophenyl)-2-<(2R)-2-(4-hydroxy-phenyl)-2-<2-(3-hydroxyphenyl)-acetylamino>acetylamino>-propionic acid methyl ester 
• 199486-38-9 11(R)-11-(4-hydroxyphenyl)-9,12-dioxo-2-oxa-10,13-diaza-tricyclo-<14.2.2.1^3,7>heneicosa-1(19),3(21),4,6(20),17-hexaene-(14S)-14-carboxylic-3-fluoro-4-nitrobenzylamine 
• 199486-39-0 11(R)-11-(4-hydroxyphenyl)-9,12-dioxo-2-oxa-10,13-diaza-tricyclo-<14.2.2.1^3,7>heneicosa-1(19),3(21),4,6(20),17-hexaene-(14S)-14-carboxxylic acid methyl ester 
• 178744-39-3 L-4-fluoro-3-nitrophenylalanine methyl ester 
• 173775-54-7 (R)-N-(tert-butoxycarbonyl)-4-fluoro-3-nitrophenylalanine 
• 188624-30-8 (R)-N-trifluoroacetyl-4-fluoro-3-nitrophenylalanine methyl ester 
• 188624-28-4 (S)-N-trifluoroacetyl-4-fluoro-3-nitrophenylalanine 

Relevant academic research and scientific papers

Chemoenzymatic synthesis of enantiomerically pure 4-fluoro-3-nitro and 3-fluoro-4-nitro phenylallanine

Both antipodes of enantiomerically pure 4-fluoro-3-nitrophenylalanine and 3-fluoro-4-nitrophenylalanine were obtained from their corresponding racemates via enzymatic resolution.

The first synthesis of 16+15-membered bicyclic polypeptide model of A- O-C-B-O-D rings of kistamicin

A 16+15 membered bicyclic polypeptide containing biaryl ether bonds, model of A-O-C-B-O-D rings of kistamicin has been synthesized by sequential intramolecular SN(Ar) reactions.