188641-36-3

Upstream product

• 173724-94-2 (S)-5-Oxo-1-((S)-1-phenyl-ethyl)-pyrrolidine-3-carbaldehyde 
• 173724-93-1 (4R,1'S)-4-ethenyl-1-(1'-phenyleth-1'-yl)pyrrolidin-2-one 
• 124-63-0 methanesulfonyl chloride 
• 188641-35-2 (4S,1'S)-4-hydroxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 

Downstream Products

• 169532-12-1 (1R,5S)-3-aza-2-oxobicyclo<3.1.0>hexane 
• 188641-37-4 (1'S,1R,5S)-3-(1-phenyleth-1'-yl)-3-aza-bicyclo[3.1.0]hexan-2-one 

Relevant academic research and scientific papers

From 3-aza-2-oxobicyclo[3.1.0]hexane to enantiopure disubstituted cyclopropane: A convenient approach to cis-2,3-methano-GABA

Starting from the diastereomerically pure 4-ethenyl pyrrolidin-2-one 5, through simple steps the mesyl derivative 8 was obtained, which underwent intramolecular alkylation to give, in good yield, the 3-aza-2-oxobicyclo[3.1.0]hexane 9. This compound was su