From 3-aza-2-oxobicyclo[3.1.0]hexane to enantiopure disubstituted cyclopropane: A convenient approach to cis-2,3-methano-GABA

DOI: 10.1016/S0957-4166(96)00477-6

Source and publish data:

Tetrahedron Asymmetry p. 133 - 137 (1997)

Update date:2022-08-04

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Authors:

Galeazzi, Roberta

Mobbili, Giovanna

Orena, Mario

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Article abstract of DOI:10.1016/S0957-4166(96)00477-6

Starting from the diastereomerically pure 4-ethenyl pyrrolidin-2-one 5, through simple steps the mesyl derivative 8 was obtained, which underwent intramolecular alkylation to give, in good yield, the 3-aza-2-oxobicyclo[3.1.0]hexane 9. This compound was su

Full text of DOI:10.1016/S0957-4166(96)00477-6

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