188758-93-2

Basic information

• Product Name: 4-amino-N-[2-(dimethylamino)ethyl]benzamide
• Synonyms: 4-amino-N-[2-(dimethylamino)ethyl]benzamide
• CAS NO: 188758-93-2
• Molecular Formula: C₁₁H₁₇N₃O
• Molecular Weight: 207.27218
• Mol File: 188758-93-2.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-amino-N-[2-(dimethylamino)ethyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-N-[2-(dimethylamino)ethyl]benzamide(188758-93-2)
• EPA Substance Registry System: 4-amino-N-[2-(dimethylamino)ethyl]benzamide(188758-93-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 188758-93-2(Hazardous Substances Data)

Upstream product

• 150-13-0 4-amino-benzoic acid 
• 108-00-9 N,N-dimethylethylenediamine 
• 62-23-7 4-nitro-benzoic acid 
• 122-04-3 4-nitro-benzoyl chloride 
• 347907-60-2 N-(2-(dimethylamino)ethyl)-4-nitrobenzamide 

Downstream Products

• 1173207-65-2 N-[2-(dimethylamino)ethyl]-4-[({4-[3-(1-methylethyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl]phenyl}carbamoyl)amino]benzamide 
• 1173207-55-0 methyl 3-[5-(4-{[(4-{[2-(dimethylamino)ethyl]carbamoyl}phenyl)carbamoyl]amino}phenyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]benzoate 
• 1197165-22-2 4-(3-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-(tetrahydro-2H-pyran-4-yl)-1,3,5-triazin-2-yl)phenyl)ureido)-N-(2-(dimethylamino)ethyl)benzamide 
• 1197162-30-3 N-[2-(dimethylamino)ethyl]-4-({[4-(4-isopropoxy-6-morpholin-4-yl-1,3,5-triazin-2-yl)phenyl]carbamoyl}amino)benzamide 
• 1197162-86-9 N-[2-(dimethylamino)ethyl]-4-({[4-(4-methoxy-6-morpholin-4-yl-1,3,5-triazin-2-yl)phenyl]carbamoyl}amino)benzamide 
• 1201691-22-6 4-(9-cyclobutyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-N-(2-dimethylamino-ethyl)-benzamide 
• 466694-48-4 methyl 3-(Z)-[1-{4-[(2-dimethylamino-ethyl)-carbamoyl]-phenylamino}-1-phenyl-methylidene]-2-indolinone-6-carboxylate 
• 1310570-12-7 4-(3-chloro-7-methoxyfuro[2,3-b]quinolin-4-ylamino)-N-(2-dimethylaminoethyl)benzamide 

Relevant articles and documents

High Turnover Pd/C Catalyst for Nitro Group Reductions in Water. One-Pot Sequences and Syntheses of Pharmaceutical Intermediates

Commercially available Pd/C can be used as a catalyst for nitro group reductions with only 0.4 mol % Pd loading. The reaction can be performed using either silane as a transfer hydrogenating agent or simply a hydrogen balloon (μ1 atm pressure). With this technology, a series of nitro compounds was reduced to the desired amines in high chemical yields. Both the catalyst and surfactant were recycled several times without loss of reactivity.

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