188774-17-6

Upstream product

• 188774-03-0 5,8-Dimethoxy-4-phenyl-3,4-dihydro-1H-quinolin-2-one 
• 128500-58-3 N-(2-methoxy-5-nitrophenyl)-3-oxo-3-phenylpropanamide 
• 312325-54-5 N-(5-acetamido-2-methoxyphenyl)-3-hydroxy-3-phenylpropanamide 
• 188773-93-5 2-{[2-(2,2-Dimethyl-propionylamino)-3,6-dimethoxy-phenyl]-phenyl-methyl}-malonic acid diisopropyl ester 
• 188773-99-1 2-{[2-(2,2-Dimethyl-propionylamino)-3,6-dimethoxy-phenyl]-phenyl-methyl}-malonic acid diethyl ester 
• 170959-02-1 2,5-dimethoxypivaloylaminobenzene 
• 5292-53-5 diethyl benzalmalonate 
• 155306-02-8 diisopropyl 2-(phenylmethylidene)malonate 
• 312325-53-4 N-(5-amino-2-methoxyphenyl)-3-hydroxy-3-phenylpropanamide 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 312325-56-7 5-amino-3,4-dihydro-8-methoxy-4-phenylquinolin-2(1H)-one 
• 312325-55-6 5-acetamido-3,4-dihydro-8-methoxy-4-phenylquinolin-2(1H)-one 
• 99-59-2 3-amino-4-methoxynitrobenzene 

Relevant academic research and scientific papers

The synthesis of pyrido(2,3,4-,kl)acridine unit of some marine alkaloids

A simple and convenient synthesis of pyrido(2,3,4-kl)acridine (1), the main skeleton of some marine alkaloids, via cyclization and intramolecular nitrene insertion, is described. The importance of the planarity of the molecule during the nitrene insertion

Synthesis and reactivity of michael adducts of lithiated 2,5-dimethoxy-N-pivaloylanilines and arylidenemalonates

Michael addition of lithiated 2,5-dimethoxypivaloylaniline to diisopropyl arylidenmalonates, followed by acid cyclization, affords 5,8-dimethoxy-4-aryl-3,4-dihydro-2(1H)quinolinones (5). These compounds are very inert to the 3,4-dehydrogenation, but were easily transformed to 4-aryl-3,4-dihydro-(1H)quinoline-2,5,8-triones (10) which, through Diels-Alder heterocyclization, gave 4-aryl-3,4-dihydro-1,8-diazaanthracene-2,9,10-triones (16).