188844-71-5Relevant academic research and scientific papers
Copper(ii)-catalyzed c-n coupling of aryl halides and n-nucleophiles promoted by quebrachitol or diethylene glycol
Chen, Guoliang,Chen, Yuanguang,Du, Fangyu,Fu, Yang,Wu, Ying,Zhou, Qifan
supporting information, p. 2161 - 2168 (2019/11/25)
Herein, we report the natural ligand quebrachitol (QCT) as a promoter for a Cu(II) catalyst, which is highly effective for N-Arylation of various amines and related aryl halides. A series of diarylamine derivatives were obtained in high yields by using diethylene glycol (DEG) as both ligand and solvent. The C-N coupling reactions proceed under mild conditions and exhibit good functional group tolerance.
11-PHENYL-DIBENZODIAZEPINE DERIVATIVES AS RXR-ANTAGONISTS
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Page 24, (2010/02/09)
The present invention relates to novel benzodiazepine compounds exhibiting RXR-antagonist efficacy, for delaying progression of, preventing or treating a condition or disease being associated with RXR-antagonism, in particular selected from diabetes, comp
Retinoid X receptor-antagonistic diazepinylbenzoic acids
Ebisawa, Masayuki,Umemiya, Hiroki,Ohta, Kiminori,Fukasawa, Hiroshi,Kawachi, Emiko,Christoffel, Ghislaine,Gronemeyer, Hinrich,Tsuji, Motonori,Hashimoto, Yuichi,Shudo, Koichi,Kagechika, Hiroyuki
, p. 1778 - 1786 (2007/10/03)
Several dibenzodiazepine derivatives were identified as novel retinoid X receptor (RXR) antagonists on the basis of inhibitory activity on retinoid- induced cell differentiation of human promyelocytic leukemia cells HL-60 and transactivation assay using r
